Evidence map›Paper›PMID 36870988›Full record

ArticleJournal of the American Heart Association2023

Always Look on the Bright Side: Associations of Optimism With Functional Outcomes After Stroke.

Kelly L Sloane, Scott E Kasner, Christopher G Favilla, Aaron Rothstein, Jens Witsch, Roy H Hamilton, Andrea L C Schneider

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kelly L SloaneDepartment of Neurology University of Pennsylvania Perelman School of Medicine Philadelphia PA USA.ORCID 0000-0001-9680-9565
Scott E KasnerDepartment of Neurology University of Pennsylvania Perelman School of Medicine Philadelphia PA USA.ORCID 0000-0003-0418-6917
Christopher G FavillaDepartment of Neurology University of Pennsylvania Perelman School of Medicine Philadelphia PA USA.ORCID 0000-0003-0871-9549
Aaron RothsteinDepartment of Neurology University of Pennsylvania Perelman School of Medicine Philadelphia PA USA.ORCID 0000-0002-8480-8220
Jens WitschDepartment of Neurology University of Pennsylvania Perelman School of Medicine Philadelphia PA USA.ORCID 0000-0001-8924-851X
Roy H HamiltonDepartment of Neurology University of Pennsylvania Perelman School of Medicine Philadelphia PA USA.ORCID 0000-0002-9958-1946
Andrea L C SchneiderDepartment of Neurology University of Pennsylvania Perelman School of Medicine Philadelphia PA USA.ORCID 0000-0003-0026-5052
University of Pennsylvania · US

Funding

Institutional Clinical and Translational Science AwardKL2TR001879 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI MEAGHER, EMMA ANNE · 2016 to 2025
$13.7M
Establishing Mechanisms Between Traumatic Brain Injury and Dementia Using Epidemiology, Clinical Studies, Blood-Based Biomarkers, and Neuroimaging BiomarkersK23NS123340 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Andrea Lauren Christman Schneider · 2022 to 2026
$1.1M
NCATS NIH HHS KL2 TR001879NINDS NIH HHS K23 NS123340
6 · The paper itself

Abstract

Background Psychological health is as an important contributor to recovery after cardiovascular disease, but the roles of both optimism and depression in stroke recovery are not well characterized. Methods and Results A total of 879 participants in the SRUP (Stroke Recovery in Underserved Populations) 2005 to 2006 Study, aged ≥50 years, with incident stroke admitted to a rehabilitation facility were included. Optimism was assessed by the question: "Are you optimistic about the future?" Depression was defined by Center for Epidemiologic Studies Depression scale score >16. Participants were categorized into 4 groups: optimistic/without depression (n=581), optimistic/with depression (n=197), nonoptimistic/without depression (n=36), and nonoptimistic/with depression (n=65). Functional Independence Measure scores were used to assess stroke outcomes at discharge, 3 months after discharge, and 1 year after discharge with adjusted linear mixed models to estimate score trajectories. Participants were a mean age of 68 years (SD, 13 years), 52% were women, and 74% were White race. The optimistic/without depression group experienced the most recovery of total Functional Independence Measure scores in the first 3 months, 24.0 (95% CI, 22.5-25.4), followed by no change in the following 9 months, -0.3 (95% CI, -2.3 to 1.7), similar to the optimistic/with depression group with rapid recovery in 0 to 3 months, 21.1 (95% CI, 18.6-23.6) followed by minimal change in 3 to 12 months, 0.7 (95% CI, -2.8 to 4.1). The nonoptimistic groups demonstrated slow but continued recovery throughout the 12-month period, with overall change, 25.4 (95% CI, 17.6-33.2) in the nonoptimistic/without depression group and 17.6 (95% CI, 12.0-23.1) in the nonoptimistic/with depression group. There was robust effect modification between optimism and depression (

Indexed as

Cardiovascular DiseasesStrokeAgedFemaleHospitalizationHumansLinear ModelsMaleMental Healthpsychological healthrecoveryrehabilitationstroke

Identifiers

PMID36870988
PMCPMC10111448
OpenAlexW4323073412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.