Evidence map›Paper›PMID 36870740›Full record

ArticleIndian journal of medical microbiology

Cytomegalovirus reactivation in a SARS-CoV-2 infected woman experiencing fetal demise in the first trimester with fetal trisomy 21: A case report.

Shailesh Pande, Manisha Gandhewar, Pradeep Gaikwad, Prajakta Shende, Kiran Munne, Vikrant M Bhor, Dhanjit Das, Dolly Bashani, Manasi Bhase, Amisha Rathore and 8 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Indian journal of medical microbiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Shailesh PandeGenetic Research Centre, ICMR-National Institute for Research in Reproductive and Child Health (ICMR-NIRRCH), Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: pandes@nirrh.res.in.
Manisha GandhewarDepartment of Obstetrics and Gynecology, ESI-PGIMSR and Model Hospital Andheri, E.S.I.S. Hospital Kandivali, Mumbai, India. Electronic address: manisharajesh@gmail.com.
Pradeep GaikwadDepartment of Obstetrics and Gynecology, ESI-PGIMSR and Model Hospital Andheri, E.S.I.S. Hospital Kandivali, Mumbai, India. Electronic address: drpradiprgaikwad@gmail.com.
Prajakta ShendeDepartment of Obstetrics and Gynecology, ESI-PGIMSR and Model Hospital Andheri, E.S.I.S. Hospital Kandivali, Mumbai, India. Electronic address: praj.shende@gmail.com.
Kiran MunneDepartment of Clinical Research, ICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: munnek@nirrh.res.in.
Vikrant M BhorMolecular Immunology and Microbiology, ICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: bhorv@nirrh.res.in.
Dhanjit DasDepartment of Stem Cell Biology, ICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: dasd@nirrh.res.in.
Dolly BashaniDepartment of Obstetrics and Gynecology, ESI-PGIMSR and Model Hospital Andheri, E.S.I.S. Hospital Kandivali, Mumbai, India. Electronic address: dollybashani91@gmail.com.
Manasi BhaseDepartment of Obstetrics and Gynecology, ESI-PGIMSR and Model Hospital Andheri, E.S.I.S. Hospital Kandivali, Mumbai, India. Electronic address: bhasemanasi@gmail.com.
Amisha RathoreDepartment of Obstetrics and Gynecology, ESI-PGIMSR and Model Hospital Andheri, E.S.I.S. Hospital Kandivali, Mumbai, India. Electronic address: rathoreamisha@gmail.com.
Karan ShahMolecular Immunology and Microbiology, ICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: karan.ang@gmail.com.
Harshavardhan GawdeGenetic Research Centre, ICMR-National Institute for Research in Reproductive and Child Health (ICMR-NIRRCH), Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: harsh.gawde@gmail.com.
Varsha PadwalDepartment of Viral Immunopathogenesis, ICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: padwal.varsha@gmail.com.
Sharad BhagatDepartment of Viral Immunopathogenesis, ICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: sharadbiotech@gmail.com.
Shyla MenonDepartment of Stem Cell Biology, ICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: shyla.ravindran@gmail.com.
Harsha PalavDepartment of Viral Immunopathogenesis, ICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: harshapalav1@gmail.com.
Geetanjali SachdevaICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: sachdevag@nirrh.res.in.
Vainav PatelDepartment of Viral Immunopathogenesis, ICMR-NIRRCH, Jehangir Merwanji Street, Parel, Mumbai 400012, India. Electronic address: patelv@nirrh.res.in.
National Institute for Research in Reproductive Health · INEmployees State Insurance Post Graduate Institute of Medical Sciences and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytomegalovirus (CMV) is the most common cause of congenital viral infections. Women seropositive for CMV prior to pregnancy can develop a non-primary CMV infection. Here, we present a case of first trimester pregnancy loss during active SARS-CoV-2 infection. There was no evidence of SARS-CoV-2 RNA in placenta and fetal tissue, but there was presence of congenital cytomegalovirus infection by nested PCR. To the best of our knowledge, this is the first report demonstrating association of early congenital CMV infection due to reactivation and fetal demise in a SARS-CoV-2 positive woman with fetal trisomy 21.

Indexed as

COVID-19Cytomegalovirus InfectionsDown SyndromeCytomegalovirusFemaleFetal DeathFetusHumansPregnancyPregnancy Trimester, FirstRNA, ViralSARS-CoV-2RNA, ViralCongenital cytomegalovirus infectionSARS-CoV-2Trisomy-21

Identifiers

PMID36870740
PMCPMC9780583
OpenAlexW4312110169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.