Evidence map›Paper›PMID 36870029›Full record

ArticleAging clinical and experimental research2023

Assessing cognitive impairment in an ethnically diverse cohort of oldest-old: the life after 90 study.

Diana Petrosyan, Maria M Corrada, Claudia H Kawas, Asmeret Demoz, Czarina Ganzon, Oksana Popovich, Reham Gaied, Dan Mungas, Paola Gilsanz, Katharine E Vieira and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 citations in OpenAlex.

  1. Neuropathology in a diverse cohort of oldest-old: The LifeAfter90 study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Cognitive screening biases in a secondary prevention Alzheimer's disease clinical trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Association of Depression Dimensions With Cognitive Functioning in Community-Dwelling Oldest-Old Adults: The LifeAfter90 Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Diana PetrosyanSchool of Medicine, Department of Neurology, University of California at Davis, 4860 Y Street, Suite 3700, Sacramento, CA, 95817, USA.
Maria M CorradaSchool of Medicine, Department of Neurology, University of California at Irvine, Irvine, CA, 92617, USA.
Claudia H KawasSchool of Medicine, Department of Neurology, University of California at Irvine, Irvine, CA, 92617, USA.
Asmeret DemozSchool of Medicine, Department of Neurology, University of California at Davis, 4860 Y Street, Suite 3700, Sacramento, CA, 95817, USA.
Czarina GanzonSchool of Medicine, Department of Neurology, University of California at Davis, 4860 Y Street, Suite 3700, Sacramento, CA, 95817, USA.
Oksana PopovichSchool of Medicine, Department of Neurology, University of California at Davis, 4860 Y Street, Suite 3700, Sacramento, CA, 95817, USA.
Reham GaiedSchool of Medicine, Department of Neurology, University of California at Davis, 4860 Y Street, Suite 3700, Sacramento, CA, 95817, USA.
Dan MungasSchool of Medicine, Department of Neurology, University of California at Davis, 4860 Y Street, Suite 3700, Sacramento, CA, 95817, USA.
Paola GilsanzKaiser Permanente Division of Research, Oakland, CA, 94612, USA.
Katharine E VieiraKaiser Permanente Division of Research, Oakland, CA, 94612, USA.
Rachel A WhitmerSchool of Medicine, Department of Neurology, University of California at Davis, 4860 Y Street, Suite 3700, Sacramento, CA, 95817, USA.
Charles DeCarliSchool of Medicine, Department of Neurology, University of California at Davis, 4860 Y Street, Suite 3700, Sacramento, CA, 95817, USA. cdecarli@ucdavis.edu.ORCID http://orcid.org/0000-0003-1914-2693
University of California, Davis · USKaiser Permanente · USUniversity of California, Irvine · US

Funding

Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in Cohort of Oldest-OldR01AG056519 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Maria Corrada, Paola Gilsanz · 2022 to 2026
$25.8M
UC Davis Alzheimer's Disease Research CenterP30AG072972 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Charles DeCarli, Rachel A Whitmer · 2021 to 2026
$25.2M
Epidemiology of Age-related Dementia, Mild Cognitive Impairment and Brain Pathology in a Multiethnic Cohort of Oldest-Old - Administrative SupplementRF1AG056519 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CORRADA, MARIA, WHITMER, RACHEL A · 2017 to 2020
$13.4M
NIA NIH HHS P30 AG072972NIA NIH HHS R01 AG056519NIA NIH HHS RF1 AG056519
6 · The paper itself

Abstract

backgroundThough dementia rates vary by racial or ethnic groups, it is unknown if these disparities remain among those aged 90 or older.

aimsTo test this hypothesis, we used baseline clinical evaluation of 541 ethnically and racially diverse individuals participating in the LifeAfter90 Study to assess how associations between core demographic characteristics and measures of physical and cognitive performance differ across the racial/ethnic groups.

methodsParticipants in this study were long-term non-demented members of Kaiser Permanente Northern California. They were clinically evaluated and diagnosed with normal or impaired cognition (mild cognitive impairment and dementia) through an in-person comprehensive clinical assessment consisting of a detailed medical history, physical and neurological examination, functional, and cognitive tests.

resultsThe average age at enrollment was 93.0 ± 2.6 years, 62.4% female and 34.2% non-Hispanic White. At initial evaluation 301 participants had normal cognition and 165 had mild cognitive impairment (MCI) and despite screening, 69 participants were determined to have dementia. Age, education, 3MS, FAQ and CDR scores were significantly associated with cognitive impairment (normal versus MCI and dementia), but not gender. There was a significant univariate association between race/ethnicity and cognitive impairment (p < 0.02) being highest among Black (57.4%) and lowest among Asian (32.7%) individuals. After adjustment for age, gender, and education, however, prevalence of cognitive impairment was not influenced by race or ethnicity.

conclusionOur results confirm the ability to reliably assess clinical diagnosis in a diverse sample of very old individuals.

Indexed as

Cognition DisordersCognitive DysfunctionDementiaAged, 80 and overCognitionFemaleHumansMaleNeuropsychological Tests3MSCognitive impairmentCognitive testingDiverse populationEpidemiologyOldest-old

Identifiers

PMID36870029
PMCPMC10149459
OpenAlexW4323067204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.