Evidence map›Paper›PMID 36870015›Full record

ArticleJournal of endocrinological investigation2023

Retinal sensitivity and gaze fixation evaluated by microperimetry in subjects with type 2 diabetes: two independent parameters that explore different neuronal circuits.

A M Ortiz-Zuñiga, A Rojano Toimil, K Rahnama, E Lainez, N Raguer, O Simó-Servat, C Hernández, R Simó, A Ciudin

Open access · hybridAbstract read
In one paragraph

Article in Journal of endocrinological investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

A M Ortiz-ZuñigaDepartment of Endocrinology and Nutrition, Hospital Universitari Vall Hebron, Pg Vall Hebron 119-129, 08035, Barcelona, Spain.
A Rojano ToimilDepartment of Endocrinology and Nutrition, Hospital Universitari Vall Hebron, Pg Vall Hebron 119-129, 08035, Barcelona, Spain.
K RahnamaDepartment of Clinical Neurophysiology, Hospital Universitari Vall Hebron, Pg Vall Hebron 119-129, 08035, Barcelona, Spain.
E LainezDepartment of Clinical Neurophysiology, Hospital Universitari Vall Hebron, Pg Vall Hebron 119-129, 08035, Barcelona, Spain.
N RaguerDepartment of Clinical Neurophysiology, Hospital Universitari Vall Hebron, Pg Vall Hebron 119-129, 08035, Barcelona, Spain.
O Simó-ServatDepartment of Endocrinology and Nutrition, Hospital Universitari Vall Hebron, Pg Vall Hebron 119-129, 08035, Barcelona, Spain.
C HernándezDepartment of Endocrinology and Nutrition, Hospital Universitari Vall Hebron, Pg Vall Hebron 119-129, 08035, Barcelona, Spain.
R SimóDepartment of Endocrinology and Nutrition, Hospital Universitari Vall Hebron, Pg Vall Hebron 119-129, 08035, Barcelona, Spain. rafael.simo@vhir.org.ORCID http://orcid.org/0000-0003-0475-3096
A CiudinDepartment of Endocrinology and Nutrition, Hospital Universitari Vall Hebron, Pg Vall Hebron 119-129, 08035, Barcelona, Spain. andreea.ciudin@vallhebron.cat.ORCID http://orcid.org/0000-0001-5622-0203
Universitat Autònoma de Barcelona · ESVall d'Hebron Hospital Universitari · ESHebron University · PS

Funding

Instituto de Salud Carlos III PI20/01703
6 · The paper itself

Abstract

BACKGROUND AND

aimsRetinal sensitivity (RS) and gaze fixation (GF) assessed by retinal microperimetry are useful and complementary tools for identifying mild cognitive impairment (MCI) in patients with type 2 diabetes (T2D). The hypothesis is that RS and GF examine different neural circuits: RS depends only on the visual pathway while GF reflects white matter complex connectivity networks. The aim of the study is to shed light to this issue by examining the relationship of these two parameters with visual evoked potentials (VEP), the current gold standard to examine the visual pathway. MATERIALS AND

methodsConsecutive T2D patients > 65 years were recruited from the outpatient clinic. Retinal microperimetry (MAIA 3rd generation) and visual evoked potentials (VEP) (Nicolet Viking ED). RS (dB), GF (BCEA63%, BCEA95%) (MAIA) and VEP (Latency P100ms, Amplitude75-100 uV) were analyzed.

resultsThirty three patients (45% women, 72.1 ± 4.6 years) were included. VEP parameters significantly correlated with RS but not with GF.

conclusionsThese results confirm that RS but not GF depends on the visual pathway, reinforcing the concept that they are complementary diagnostic tools. Used together can further increase the value of microperimetry as screening test for identifying T2D population with cognitive impairment.

Indexed as

Diabetes Mellitus, Type 2Visual Field TestsEvoked Potentials, VisualFemaleHumansMaleRetinaVisual FieldsGaze fixationRetinal microperimetryRetinal sensitivityType 2 diabetesVisual evoked potentials

Identifiers

PMID36870015
PMCPMC10371889
OpenAlexW4323067117

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.