ArticleEuropean journal of nutrition2023
Dietary Inflammatory Index and risk of breast cancer: evidence from a prospective cohort of 67,879 women followed for 20 years in France.
Article in European journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Associations Between Dietary Factors and Breast Cancer Risk: A Systematic Review of Evidence from the MENA Region.Nutrients · 2025Pooled it
- Associations of the Endothelial Activation and Stress Index with breast cancer prevalence and mortality based on NHANES 2001 to 2018.Medicine · 2026Article
- Association between the dietary inflammatory index and pregnancy outcomes in women with gestational diabetes mellitus: a prospective cohort study.Frontiers in nutrition · 2026Article
- The association between the Dietary Inflammatory Index and breast cancer risk: an updated systematic review and meta-analysis.Frontiers in nutrition · 2026Review
- Proinflammatory dietary pattern and risk of total and subtypes of breast cancer among US women.Journal of the National Cancer Institute · 2025Article
- L-shaped association of dietary inflammatory index (DII) and chronic diarrhea: results from NHANES 2005-2010.BMC public health · 2025Article
- The relationship between the neutrophil percentage to albumin ratio and the occurrence of prostate cancer.PloS one · 2025Article
- Association between neutrophil percentage-to-albumin ratio and breast cancer in adult women in the US: findings from the NHANES.Frontiers in nutrition · 2025Article
- Non-linear relationship between the dietary inflammatory index and stroke risk in metabolically healthy obese individuals: an analysis of NHANES 1999-2023 data.Frontiers in nutrition · 2025Article
- Combined influence of nutritional and inflammatory status and breast cancer: findings from the NHANES.BMC public health · 2024Article
- Dietary Patterns Associated with Breast Cancer in the Middle East: A Scoping Review.Nutrients · 2024Article
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammation is implicated in breast cancer development, and diet is one of the modifiable risk factors involved in the regulation of chronic inflammation. Previous studies on the association between breast cancer risk and Dietary Inflammatory Indexes (DII) derived from food frequency questionnaires and data on inflammatory potential of dietary components have reported inconsistent results.
objectiveTo investigate the association between the DII and the risk of breast cancer using data from a large population-based cohort study.
designA total of 67,879 women from the E3N cohort were followed from 1993 to 2014. A total of 5686 breast cancer cases were diagnosed during the follow-up. The food frequency questionnaire administered at baseline in 1993 was used to calculate an adapted DII. Cox proportional hazard models using age as the time scale were used to estimate hazard ratios (HR) and 95% confidence intervals (CI). Spline regression was used to determine any dose-response relationship. We also evaluated effect modification by menopausal status, body mass index, smoking status and alcohol consumption.
resultsThe median DII score of the study population was slightly pro-inflammatory (DII = + 0.39); ranged from - 4.68 in the lowest quintile to + 4.29 in the highest quintile. The HR increased linearly with the DII (HR per 1SD = 1.04 [95% CI: 1.01, 1.07]), and reached 1.13 [95% CI: 1.04, 1.23] in the 5th quintile group as compared to the first. A positive linear dose-response relationship was also observed when modeling DII with spline functions. Slightly higher HRs were observed in non-smokers (HR
conclusionOur results suggest a positive association between DII and breast cancer risk. Consequently, the promotion of anti-inflammatory diet may contribute to breast cancer prevention.
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