Evidence map›Paper›PMID 36869679›Full record

ArticleCardiovascular research2023

A unifying mechanism for the initiation of torsade de pointes: blurring the distinction between trigger and substrate.

Margaret McKay, Fadi G Akar

Abstract readEditorialComment
PubMed Publisher
In one paragraph

Article in Cardiovascular research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Primary Electrical Heart Disease-Principles of Pathophysiology and Genetics.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Margaret McKayDepartment of Biomedical Engineering, Yale University Schools of Engineering and Applied Sciences, 300 George Street, New Haven, CT 793-748C, USA.
Fadi G AkarDepartment of Biomedical Engineering, Yale University Schools of Engineering and Applied Sciences, 300 George Street, New Haven, CT 793-748C, USA.ORCID 0000-0001-9146-8407

Funding

Metabolic signaling in atrial fibrillation and remodelingR01HL148008 · NHLBI · YALE UNIVERSITY · PI AKAR, FADI GABRIEL, YOUNG, LAWRENCE H · 2021 to 2024
$2.2M
Mitochondrial fission in diabetes-related arrhythmiaR01HL149344 · NHLBI · YALE UNIVERSITY · PI AKAR, FADI GABRIEL · 2020 to 2023
$1.7M
Optimizing AF ablation by a novel optogenetics and computational approachR21HL165147 · NHLBI · YALE UNIVERSITY · PI AKAR, FADI GABRIEL · 2022 to 2023
$461k
NHLBI NIH HHS R01 HL148008NHLBI NIH HHS R01 HL149344NHLBI NIH HHS R21 HL165147
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Long QT SyndromeTorsades de PointesArrhythmias, CardiacCognitionHumans

Identifiers

PMID36869679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.