Evidence map›Paper›PMID 36869330›Full record

ArticleBMC musculoskeletal disorders2023

(Cost-)effectiveness of a personalized multidisciplinary eHealth intervention for knee arthroplasty patients to enhance return to activities of daily life, work and sports - rationale and protocol of the multicentre ACTIVE randomized controlled trial.

A Carlien Straat, Jantine M Maarleveld, Denise J M Smit, Lara Visch, Gerben Hulsegge, Judith A F Huirne, J M van Dongen, Rutger C van Geenen, Gino M M J Kerkhoffs, Johannes R Anema and 2 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Implementation of +PERTOHealthcare (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Best practice in digital orthopaedics.EFORT open reviews · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

A Carlien StraatAmsterdam UMC, Department of Public and Occupational Health, Van Der Boechorststraat 7, Amsterdam, 1081 BT, the Netherlands.
Jantine M MaarleveldAmsterdam UMC, Department of Public and Occupational Health, Van Der Boechorststraat 7, Amsterdam, 1081 BT, the Netherlands.
Denise J M SmitAmsterdam UMC, Department of Public and Occupational Health, Van Der Boechorststraat 7, Amsterdam, 1081 BT, the Netherlands.
Lara VischDepartment of Research, Sint Maartenskliniek, Nijmegen, The Netherlands.
Gerben HulseggeSustainable Productivity & Employability, Netherlands Organization for Applied Scientific Research TNO, Leiden, the Netherlands.
Judith A F HuirneDepartment of Obstetrics and Gynecology, Amsterdam UMC, Location VU Medical Center, Amsterdam, The Netherlands.
J M van DongenDepartment of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences Research Institute, Amsterdam, The Netherlands.
Rutger C van GeenenDepartment of Orthopaedic Surgery, FORCE (Foundation for Orthopaedic Research Care Education), Amphia Hospital, Breda, The Netherlands.
Gino M M J KerkhoffsDepartment of Orthopaedic Surgery and Sports Medicine, Amsterdam Movement Sciences, Amsterdam University Medical Center, Location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Johannes R AnemaAmsterdam UMC, Department of Public and Occupational Health, Van Der Boechorststraat 7, Amsterdam, 1081 BT, the Netherlands.
Pieter Coenen *Amsterdam UMC, Department of Public and Occupational Health, Van Der Boechorststraat 7, Amsterdam, 1081 BT, the Netherlands. p.coenen@amsterdamumc.nl.
P Paul F M KuijerAmsterdam UMC, Department of Public and Occupational Health, Van Der Boechorststraat 7, Amsterdam, 1081 BT, the Netherlands.
Health & Safety in Sports · NLAmphia Ziekenhuis · NLAmsterdam UMC Location Vrije Universiteit Amsterdam · NLAmsterdam University Medical Centers · NLNational Institute for Public Health and the Environment · NLNetherlands Organisation for Applied Scientific Research · NLPublic Health Service of Amsterdam · NLSint Maartenskliniek · NLVrije Universiteit Amsterdam · NL

Funding

ZonMw 852001929
6 · The paper itself

Abstract

backgroundWith the worldwide rising obesity epidemic and the aging population, it is essential to deliver (cost-)effective care that results in enhanced societal participation among knee arthroplasty patients. The purpose of this study is to describe the development, content, and protocol of our (cost-)effectiveness study that assesses a perioperative integrated care program, including a personalized eHealth app, for knee arthroplasty patients aimed to enhance societal participation post-surgery compared to care as usual.

methodsThe intervention will be tested in a multicentre randomized controlled trial with eleven participating Dutch medical centers (i.e., hospitals and clinics). Working patients on the waiting-list for a total- or unicompartmental knee arthroplasty with the intention to return to work after surgery will be included. After pre-stratification on medical centre with or without eHealth as usual care, operation procedure (total- or unicompartmental knee arthroplasty) and recovery expectations regarding return to work, randomization will take place at the patient-level. A minimum of 138 patients will be included in both the intervention and control group, 276 in total. The control group will receive usual care. On top of care as usual, patients in the intervention group will receive an intervention consisting of three components: 1) a personalized eHealth intervention called ikHerstel ('I Recover') including an activity tracker, 2) goal setting using goal attainment scaling to improve rehabilitation and 3) a referral to a case-manager. Our main outcome is quality of life, based on patient-reported physical functioning (using PROMIS-PF). (Cost-)effectiveness will be assessed from a healthcare and societal perspective. Data collection has been started in 2020 and is expected to finish in 2024. DISCUSSION: Improving societal participation for knee arthroplasty is relevant for patients, health care providers, employers and society. This multicentre randomized controlled trial will evaluate the (cost-)effectiveness of a personalized integrated care program for knee arthroplasty patients, consisting of effective intervention components based on previous studies, compared to care as usual.

trial registrationTrialsearch.who.int; reference no. NL8525, reference date version 1: 14-04-2020.

Indexed as

Arthroplasty, Replacement, KneeTelemedicineAgedAgingEthnicityHumansMulticenter Studies as TopicQuality of LifeRandomized Controlled Trials as TopicArthroplastyCost–benefit analysisDelivery of health careFitness trackersKneeMobile applicationsQuality of lifeReplacementReturn to workTelemedicine

Identifiers

PMID36869330
PMCPMC9984288
OpenAlexW4323067205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.