ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023
Quality of life and ability to work of patients with Post-COVID syndrome in relation to the number of existing symptoms and the duration since infection up to 12 months: a cross-sectional study.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Prevalence and symptoms of Long Covid-19 in the workplace.Occupational medicine (Oxford, England) · 2025Pooled it
- Work ability and return-to-work of patients with post-COVID-19: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Effects of a symptom-titrated exercise program on fatigue and quality of life in people with post-COVID condition - a randomized controlled trial.Scientific reports · 2024Trial
- Functional outcomes of children after SARS-CoV-2 infection: An EHR-based cohort study.Journal of pediatric rehabilitation medicine · 2026Article
- Association between persistent symptoms and health-related quality of life in the post-COVID-19 condition: a cross-sectional survey in a nationally representative sample of French adults.Health and quality of life outcomes · 2026Article
- Work ability and associated factors among individuals with Post COVID-19 condition- a cross-sectional study.BMC public health · 2026Article
- Lessons from irritable bowel syndrome: potential for understanding and managing post-COVID.Frontiers in immunology · 2026Review
- Twelve-Month Health-Related Quality of Life Recovery Following COVID-19 Hospitalization: A Prospective Cohort Study from Lithuania.Medicina (Kaunas, Lithuania) · 2025Article
- Lived Experiences of New-Onset Long Covid Pain and Its Impact on Health-Related Quality of Life. A Scoping Review of Current Evidence.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Predicting work ability impairment in post COVID-19 patients: a machine learning model based on clinical parameters.Infection · 2025Article
- A patient-centered view of symptoms, functional impact, and priorities in post-COVID-19 syndrome: cross-sectional results from the Québec Action Post-COVID cohort.BMC infectious diseases · 2025Article
- Prevalence of COVID-19 and Long COVID by Industry and Occupation: Behavioral Risk Factor Surveillance System 2022.American journal of industrial medicine · 2025Article
- Persistent obstacles for return to work after COVID-19 infection - an explorative follow-up study in Sweden.Frontiers in rehabilitation sciences · 2025Article
- Factors associated with health-related quality of life 1 year after COVID-19: a cross-sectional study in Sweden.Upsala journal of medical sciences · 2025Article
- Parallel mediating effects of anxiety and depression on the relationship between sleep quality and fear of progression in individuals recovering from COVID-19.Frontiers in psychology · 2025Article
- Functional disabilities and adverse well-being by COVID-19 and Long COVID history and employment status: 2022 Behavioral Risk Factor Surveillance System.American journal of industrial medicine · 2024Article
- Prevalence and risk factors of long covid and its associated adverse work outcomes among workers in the manufacturing sector in Malaysia - a mixed-methods study protocol.Journal of health, population, and nutrition · 2024Article
- Long-term course and factors influencing work ability and return to work in post-COVID patients 12 months after inpatient rehabilitation.Journal of occupational medicine and toxicology (London, England) · 2024Article
- Impact of post-COVID symptoms on activity and participation of women and men.Scientific reports · 2024Article
- Pulmonary rehabilitation in follow-up and inpatient rehabilitation for Long COVID: twelve months of follow-up.European journal of physical and rehabilitation medicine · 2024Observational
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFollowing SARS-CoV-2 virus infection, patients may suffer from long-lasting symptoms regardless of disease severity. Preliminary results show limitations in health-related quality of life (HRQoL). The aim of this study is to show a possible change depending on the duration since infection and the accumulation of symptoms. Additionally, other possible influencing factors will be analyzed.
methodsThe study population consisted of patients (18-65 years) presenting to the Post-COVID outpatient clinic of the University Hospital Jena, Germany, between March and October 2021. The HRQoL was assessed by the use of the RehabNeQ and the SF-36. Data analysis was descriptive with frequencies, means, and/or percentages. In addition, a univariate analysis of variance was performed to show the dependence of physical and psychological HRQoL on specific factors. This was finally tested for significance at an alpha level of 5%.
resultsData from 318 patients were analyzed, most of whom had 3-6 months of infection (56%) and 5-10 symptoms persisted (60.4%). Both mental (MCS) and physical sum score (PCS) of HRQoL were significantly lower than those of the German normal population (p < .001). The number of remaining symptoms (MCS p = .0034, PCS p = .000) as well as the perceived ability to work (MCS p = .007, PCS p = .000) influenced the HRQoL.
conclusionThe HRQoL of patients with Post-COVID-syndrome is still reduced months after infection and so is their occupational performance. In particular, the number of symptoms could have an influence on this deficit, which would need to be further investigated. Further research is needed to detect other factors influencing HRQoL and to implement appropriate therapeutic interventions.
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