ReviewHypertension research : official journal of the Japanese Society of Hypertension2023
Common metabolic features of hypertension and type 2 diabetes.
Review in Hypertension research : official journal of the Japanese Society of Hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- The link between hyperuricemia and diabetes: insights from a quantitative analysis of scientific literature.Frontiers in endocrinology · 2024Pooled it
- Breakthrough drugs in the treatment of hypertension-related disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- C-Reactive Protein-to-Albumin Ratio as a Prognostic Marker in ICU Patients with Pre-Existing Hypertension and Diabetes.Journal of clinical medicine · 2026Article
- Cumulative exposure and dynamic trajectories of the C-reactive protein-triglyceride-glucose index (CTI) versus the cholesterol, high-density lipoprotein, and glucose index (CHG) for incident hypertension prediction: a national cohort study.Cardiovascular diabetology · 2026Article
- The triglyceride-glucose index for diabetic retinopathy prediction in Chinese patients with type 2 diabetes: a preliminary cross-sectional study.Frontiers in endocrinology · 2026Article
- Early-phase impact of obesity-associated stress on murine vascular smooth muscle cells depends on EGFR and sex.Communications biology · 2025Article
- Article
- Mitochondrial coupling efficiency and myofiber type related to blood pressure 22 h after high-intensity exercise in premenopausal women.European journal of applied physiology · 2025Article
- Mediation of fasting blood glucose between relative muscle strength and hypertension: insights from two cohorts.Diabetology & metabolic syndrome · 2025Article
- Article
- Unraveling the complexities of diet induced obesity and glucolipid dysfunction in metabolic syndrome.Diabetology & metabolic syndrome · 2025Review
- Correlations Between Novel Adiposity Indices and Electrocardiographic Evidence of Left Ventricular Hypertrophy in Individuals with Arterial Hypertension.Journal of personalized medicine · 2025Article
- Elevated high-sensitivity C-reactive protein and dyslipidaemia in type 2 diabetes mellitus: implications for cardiovascular risk prediction in Nigerian patients.BMC endocrine disorders · 2025Article
- Management of Diabetes Mellitus and Hypertension During Hospitalization in Maxillofacial Departments.Medicina (Kaunas, Lithuania) · 2025Article
- Risk factors for comorbid hypertension in elderly patients with type 2 diabetes.American journal of translational research · 2025Article
- Elevated mean arterial pressure and risk of impaired fasting glucose: a multicenter cohort study revealing age and sex interactions.Frontiers in endocrinology · 2025Article
- Association between triglyceride glucose-waist-adjusted waist index and incident stroke in Chinese adults: a prospective cohort study.Frontiers in nutrition · 2025Article
- Linking hypertension and TyG-WC circumference index among Indian adults: A cross-sectional study.Bioinformation · 2025Article
- Investigating Ayurvedic Strategies: An In-Depth Examination of Managing Diabetes across Different Types.Current diabetes reviews · 2025Review
- Effectiveness of an exercise and nutrition intervention for older adults with mild cognitive impairment: an open-label double-arm clinical trial.Frontiers in aging neuroscience · 2025Article
Corrections and comments
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1 author at 1 institution in 1 country.
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Abstract
Hypertension and type 2 diabetes frequently coexist, suggesting that the two diseases have common pathophysiological bases. This review describes the pathophysiological mechanisms of how type 2 diabetes is frequently associated with hypertension. Multiple common factors mediate between both diseases. Factors that induce both type 2 diabetes and hypertension include obesity-induced hyperinsulinemia, activation of the sympathetic nervous system, chronic inflammation, and changes in adipokines. Vascular complications resulting from type 2 diabetes and hypertension include endothelial dysfunction, vasodilation/constriction dysfunction of peripheral vessels and increased peripheral vascular resistance, arteriosclerosis, and chronic kidney disease. While many of these vascular complications are caused by hypertension, they also exacerbate the pathology of hypertension. In addition, insulin resistance in the vasculature blunts insulin-induced vasodilation and blood flow to skeletal muscle, which contributes to impaired glucose uptake to skeletal muscle and glucose intolerance. In obese and insulin-resistant patients, increase in the circulating fluid volume forms the major pathophysiology of elevated blood pressure. On the other hand, in non-obese and/or insulin-deficient patients, especially those in the middle- or later stages of diabetes, peripheral vascular resistance is the major pathophysiology of hypertension. The relationship between various factors involved in the pathogenesis of type 2 diabetes and hypertension. It should be noted that all the factors shown in the figure are not necessarily present simultaneously in every patient.
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