Evidence map›Paper›PMID 36868854›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Facilitation of Behavioral and Cortical Emergence from Isoflurane Anesthesia by GABAergic Neurons in Basal Forebrain.

Ping Cai, Wei-Kun Su, Jin-Sheng Zhang, Pei-Chang Liu, Feng Liu, Ren-Fu Liu, Zhang-Shu Li, Zhong-Hua Zhu, Wen-Hao Xiao, Yong-Huai Hu and 5 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. The Somatostatin Pathway Projected from the Basal Forebrain to the Lateral Habenula Promotes Isoflurane Anesthesia Recovery.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Review
  6. Basal Forebrain to Ventral Tegmental Area Glutamatergic Pathway Promotes Emergence from Isoflurane Anesthesia in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Ping CaiDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian 350108, China.
Wei-Kun SuDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian 350108, China.ORCID 0000-0002-6408-8561
Jin-Sheng ZhangDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian 350108, China.
Pei-Chang LiuDepartment of Anesthesiology, Fujian Medical University Union Hospital, Fuzhou, Fujian 350001, China.
Feng LiuDepartment of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian 350001, China.
Ren-Fu LiuSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, China.
Zhang-Shu LiSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, China.
Zhong-Hua ZhuSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, China.
Wen-Hao XiaoSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, China.
Yong-Huai HuSchool of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian 350108, China.
Hong-Da CaiDepartment Of Anesthesiology, First Affiliated Hospital of Fujian Medical University, Fujian Medical University, Fuzhou, Fujian 350001, China.
Xiao-Dan WuDepartment of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou, Fujian 350001, China.
Liang-Cheng ZhangDepartment of Anesthesiology, Fujian Medical University Union Hospital, Fuzhou, Fujian 350001, China.
Changxi YuDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian 350108, China lichen01005@163.com changxiyu@mail.fjmu.edu.cn.
Li ChenDepartment of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian 350108, China lichen01005@163.com changxiyu@mail.fjmu.edu.cn.
Fujian Medical University · CNFujian Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

General anesthesia shares many similarities with natural sleep in behavior and electroencephalogram (EEG) patterns. The latest evidence suggests that general anesthesia and sleep-wake behavior may share overlapping neural substrates. The GABAergic neurons in the basal forebrain (BF) have recently been demonstrated to play a key role in controlling wakefulness. It was hypothesized that BF GABAergic neurons may participate in the regulation of general anesthesia. Here, using

Indexed as

Basal ForebrainIsofluraneAnesthesia, GeneralAnimalsElectroencephalographyFemaleGABAergic NeuronsMaleMiceSleepIsofluranebasal forebrainfiber photometryGABAergic neuronsgeneral anesthesiaisoflurane anesthesiaoptogenetics

Identifiers

PMID36868854
PMCPMC10124952
OpenAlexW4323031747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.