Evidence map›Paper›PMID 36868472›Full record

ArticleThe journal of allergy and clinical immunology. In practice2023

Poorer Caregiver Mental and Social Health Is Associated With Worse Respiratory Outcomes in Preschool Children With Recurrent Wheezing.

Anne M Fitzpatrick, Badiallo Diani, Dio Kavalieratos, E Alison Corace, Carrie Mason, Morgan Van Dresser, Jocelyn R Grunwell

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Associations between psychosocial stress, child's anxiety, and lung function in mid-childhood.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  4. Article
  5. Portuguese Validation of the TAPQoL: A Health-Related Quality of Life Instrument for Children Aged 0-6 Years.European journal of investigation in health, psychology and education · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Anne M FitzpatrickDepartment of Pediatrics, Emory University, Atlanta, Ga; Children's Healthcare of Atlanta, Atlanta, Ga. Electronic address: anne.fitzpatrick@emory.edu.
Badiallo DianiDepartment of Biomedical Engineering, Emory University, Atlanta, Ga; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Ga.
Dio KavalieratosDepartment of Family and Preventative Medicine, Emory University, Atlanta, Ga.
E Alison CoraceChildren's Healthcare of Atlanta, Atlanta, Ga.
Carrie MasonChildren's Healthcare of Atlanta, Atlanta, Ga.
Morgan Van DresserChildren's Healthcare of Atlanta, Atlanta, Ga.
Jocelyn R GrunwellDepartment of Pediatrics, Emory University, Atlanta, Ga; Children's Healthcare of Atlanta, Atlanta, Ga.
Children's Healthcare of Atlanta · USEmory University · USGeorgia Institute of Technology · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Research Training Program Plan on Cell and Tissue Engineering (CTEng)T32GM008433 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GARCIA, ANDRES J · 1991 to 2021
$7.1M
Phenotypes and Endotypes of Preschool WheezeR01NR017939 · NINR · EMORY UNIVERSITY · PI FITZPATRICK, ANNE MENTRO · 2019 to 2023
$2.5M
T32 CTEng (Cellular and Tissue Engineering) Training ProgramT32GM145735 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI Edward A. Botchwey, Andres J Garcia · 2022 to 2026
$2.3M
Mentored patient-oriented research in preschool wheezing disordersK24NR018866 · NINR · EMORY UNIVERSITY · PI FITZPATRICK, ANNE MENTRO · 2020 to 2024
$625k
NCATS NIH HHS UL1 TR002378NIGMS NIH HHS T32 GM008433NIGMS NIH HHS T32 GM145735NINR NIH HHS K24 NR018866NINR NIH HHS R01 NR017939
6 · The paper itself

Abstract

backgroundMental and social health in caregivers of preschool children has been inadequately studied, but it may influence respiratory symptom recognition and management.

objectiveTo identify preschool caregivers at highest risk for poor mental and social health outcomes on the basis of patient-reported outcome measures.

methodsFemale caregivers 18 to 50 years old (N = 129) with a preschool child aged 12 to 59 months with recurrent wheezing and at least 1 exacerbation in the previous year completed 8 validated patient-reported outcome measures of mental and social health. k-means cluster analysis was performed using the T score for each instrument. Caregiver/child dyads were followed for 6 months. Primary outcomes included caregiver quality of life and wheezing episodes in their preschool children.

resultsThree clusters of caregivers were identified: low risk (n = 38), moderate risk (n = 56), and high risk (n = 35). The high-risk cluster had the lowest life satisfaction, meaning and purpose, and emotional support and the highest social isolation, depression, anger, perceived stress, and anxiety that persisted for more than 6 months. This cluster had the poorest quality of life and marked disparities in social determinants of health. Preschool children from caregivers in the high-risk cluster had more frequent respiratory symptoms and a higher occurrence of any wheezing episode, but a lower outpatient physician utilization for wheezing management.

conclusionsCaregiver mental and social health is associated with respiratory outcomes in preschool children. Routine assessment of mental and social health in caregivers is warranted to promote health equity and improve wheezing outcomes in preschool children.

Indexed as

CaregiversQuality of LifeAdolescentAdultAnxietyChild, PreschoolFemaleHealth PromotionHumansMiddle AgedRespiratory SoundsYoung AdultAnxietyAsthma controlCaregiver burdenDepressionDisparityMental healthPatient-reported outcomesSocial determinants of healthStressWheezing

Identifiers

PMID36868472
PMCPMC10258161
OpenAlexW4322631750

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.