Evidence map›Paper›PMID 36867691›Full record

ArticleScience advances2023

The catheterized bladder environment promotes Efg1- and Als1-dependent

Alyssa Ann La Bella, Marissa Jeme Andersen, Nicholas C Gervais, Jonathan Jesus Molina, Alex Molesan, Peter V Stuckey, Lauren Wensing, Clarissa J Nobile, Rebecca S Shapiro, Felipe Hiram Santiago-Tirado and 1 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The unique Efg1 fungal virulence regulon in the catheterized bladder environment.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Exploring the Mechanism of Tannic Acid AgainstPathogens (Basel, Switzerland) · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. CAUTIon - not all UTIs are the same.Nature reviews. Urology · 2025
    Review
  13. Article
  14. Role of Clot Formation and Plasminogen Activation in Lower Urinary Tract Pathologies.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Macrophage fate: to kill or not to kill?Infection and immunity · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Alyssa Ann La BellaDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.ORCID 0000-0001-7396-9670
Marissa Jeme AndersenDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.ORCID 0000-0002-0489-086X
Nicholas C GervaisDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.ORCID 0000-0002-9971-0031
Jonathan Jesus MolinaDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.ORCID 0000-0002-0790-9992
Alex MolesanDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.ORCID 0000-0003-0686-1365
Peter V StuckeyDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.ORCID 0000-0002-6793-2289
Lauren WensingDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.ORCID 0000-0003-3737-5474
Clarissa J NobileDepartment of Molecular and Cell Biology, University of California, Merced, Merced, CA, USA.ORCID 0000-0003-0799-6499
Rebecca S ShapiroDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.ORCID 0000-0002-7119-8865
Felipe Hiram Santiago-TiradoDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.ORCID 0000-0002-6453-4904
Ana Lidia Flores-MirelesDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN, USA.ORCID 0000-0003-4610-4246
University of Notre Dame · USUniversity of Guelph · CAUniversity of California, Merced · US

Funding

Genetic regulation of inter- and intra-species microbial community formationR35GM124594 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI NOBILE, CLARISSA JANE · 2017 to 2021
$2.0M
Understanding the role of catheter-associated protein deposition in the development of CAUTIR01DK128805 · NIDDK · UNIVERSITY OF NOTRE DAME · PI FLORES-MIRELES, ANA LIDIA, HOWELL, CAITLIN L · 2021 to 2025
$1.9M
The role of a pleiotropic drug resistance (PDR) transporter in the cryptococcal-host interactionsR21AI171742 · NIAID · UNIVERSITY OF NOTRE DAME · PI SANTIAGO-TIRADO, FELIPE H · 2023 to 2024
$430k
NIAID NIH HHS R21 AI171742NIDDK NIH HHS R01 DK128805NIGMS NIH HHS R35 GM124594
6 · The paper itself

Abstract

Catheter-associated urinary tract infections (CAUTIs) account for 40% of hospital-acquired infections (HAIs). As 20 to 50% of hospitalized patients receive catheters, CAUTIs are one of the most common HAIs, resulting in increased morbidity, mortality, and health care costs.

Indexed as

Amyotrophic Lateral SclerosisCross InfectionAdhesins, BacterialCandida albicansFibrinogenHumansUrinary BladderAdhesins, BacterialFibrinogen

Identifiers

PMID36867691
PMCPMC9984171
OpenAlexW4323031711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.