Evidence map›Paper›PMID 36867629›Full record

ArticlePloS one2023

Discordance between hyposalivation and xerostomia among community-dwelling older adults in Japan.

Ichizo Morita, Hisayoshi Morioka, Yoshikazu Abe, Taketsugu Nomura, Seiji Nakashima, Iwane Sugiura, Yujo Inagawa, Yuka Kondo, Chisato Kameyama, Kanae Kondo and 1 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
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  5. Observational
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Ichizo MoritaJapanese Red Cross Toyota College of Nursing, Toyota, Aichi, Japan.ORCID 0000-0002-2905-4200
Hisayoshi MoriokaDepartment of Public Health, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Tokushima, Japan.
Yoshikazu AbeGifu Prefecture Dental Association, Gifu, Gifu, Japan.
Taketsugu NomuraGifu Prefecture Dental Association, Gifu, Gifu, Japan.
Seiji NakashimaGifu Prefecture Dental Association, Gifu, Gifu, Japan.
Iwane SugiuraGifu Prefecture Dental Association, Gifu, Gifu, Japan.
Yujo InagawaGifu Prefecture Dental Association, Gifu, Gifu, Japan.
Yuka KondoGifu Prefecture Medical Association, Gifu, Gifu, Japan.
Chisato KameyamaGifu Pharmaceutical Association, Gifu, Gifu, Japan.
Kanae KondoJapanese Red Cross Toyota College of Nursing, Toyota, Aichi, Japan.
Naoji KobayashiJapanese Red Cross Toyota College of Nursing, Toyota, Aichi, Japan.
Gifu Prefecture Medical Association · JPJapanese Red Cross Toyota College of Nursing · JPGifu Pharmaceutical University · JPTokushima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individuals with an objective decrease in salivary flow (objective dry mouth) may not be aware of subjective dry mouth (xerostomia). However, no clear evidence exists to explain the discordance between subjective and objective dry mouth. Therefore, this cross-sectional study aimed to assess the prevalence of xerostomia and decreased salivary flow among community-dwelling elderly adults. In addition, this study assessed several potential demographic and health status determinants of the discrepancy between xerostomia and reduced salivary flow. The 215 participants in this study were community-dwelling older people aged 70 years and above who underwent dental health examinations between January-February 2019. Symptoms of xerostomia were collected in the form of a questionnaire. The unstimulated salivary flow rate (USFR) was measured by a dentist using visual inspection. The stimulated salivary flow rate (SSFR) was measured using the Saxon test. We identified 19.1% of participants as having mild-severe USFR decline with xerostomia and 19.1% as having mild-severe USFR decline without xerostomia. Additionally, 26.0% of participants had low SSFR and xerostomia, and 40.0% had low SSFR without xerostomia. Except for the age trend, no factors could be associated with the discordance between USFR measurement and xerostomia. Furthermore, no significant factors were associated with the discordance between the SSFR and xerostomia. However, females were significantly associated (OR = 2.608, 95% CI = 1.174-5.791) with low SSFR and xerostomia, as compared to males. Age was a factor that was also significantly associated (OR = 1.105, 95% CI = 1.010-1.209) with low SSFR and xerostomia. Our findings indicate that approximately 20% of the participants had low USFR without xerostomia, and 40% had low SSFR without xerostomia. This study showed that age, sex, and the number of medications may not be factors in the discrepancy between the subjective feeling of dry mouth and reduced salivary flow.

Indexed as

Independent LivingXerostomiaAgedAwarenessCross-Sectional StudiesFemaleHumansJapanMale

Identifiers

PMID36867629
PMCPMC9983907
OpenAlexW4323031804

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.