Evidence map›Paper›PMID 36867303›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2023

The effect of antiperspirant and deodorant use on acute radiation dermatitis in breast cancer patients during radiotherapy: a systematic review and meta-analysis.

Viola Salvestrini, Gustavo Nader Marta, Saverio Caini, Julie Ryan Wolf, Corina van den Hurk, Mara Beveridge, Henry Lam, Pierluigi Bonomo, Edward Chow, Tara Behroozian

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Guideline
  2. Shedding light on the management of acute radiation dermatitis: insight from the MASCC Oncodermatology study group.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 5 countries.

Viola SalvestriniCyberKnife Center, Istituto Fiorentino di Cura ed Assistenza, Florence, Italy.
Gustavo Nader MartaDepartment of Radiation Oncology, Hospital Sírio-Libanês, Sao Paulo, Brazil.
Saverio CainiCancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPO), Florence, Italy.
Julie Ryan WolfDepartments of Dermatology and Radiation Oncology, University of Rochester Medical Centre, Rochester, NY, USA.
Corina van den HurkNetherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.
Mara BeveridgeDepartment of Dermatology, University Hospitals, Cleveland, OH, USA.
Henry LamSunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Pierluigi BonomoDepartment of Radiation Oncology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.
Edward ChowDepartment of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
Tara BehroozianMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada. tara.behroozian@medportal.ca.
Azienda Ospedaliero-Universitaria Careggi · ITHospital Sírio-Libanês · BRMcMaster University · CANetherlands Comprehensive Cancer Organisation · NLPiedmont Reference Center for Epidemiology and Cancer Prevention · ITSunnybrook Health Science Centre · CAUniversity Hospitals of Cleveland · USUniversity of Rochester Medical Center · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWhile some authors have investigated the impact of antiperspirant /deodorant on the development of acute radiation dermatitis (RD) among patients undergoing radiotherapy (RT) for breast cancer, recommendations supporting the use of antiperspirant/deodorant during breast RT remain highly variable. This systematic review and meta-analysis aims to evaluate the evidence investigating the effect of antiperspirant/deodorant on the development of acute RD during post-operative breast RT.

methodsA literature search has been performed using OVID MedLine, Embase, and Cochrane databases (1946 to September 2020) to identify randomized controlled trials (RCTs) that have investigated deodorant/antiperspirant use during RT. The meta-analysis was conducted using RevMan 5.4 to calculate pooled effect sizes and 95% confidence intervals (CI).

resultsFive RCTs met the inclusion criteria. The use of antiperspirant/deodorant did not significantly affect the incidence of grade (G) 1 + RD (OR 0.81, 95% CI 0.54-1.21, p = 0.31). Prohibition of deodorant use did not significantly prevent the occurrence of G2 + acute RD (OR 0.90, 95%, CI 0.65-1.25, p = 0.53). No significant effect was reported in preventing G3 RD between the antiperspirant/deodorant and control groups (OR 0.54, 95%, CI 0.26-1.12, p = 0.10). There was no significant difference in pruritus and pain between patients undergoing skin care protocols with or without antiperspirant/deodorant (OR 0.73, 95% CI 0.29, 1.81, p = 0.50, and OR 1.05, 95% CI 0.43-2.52, p = 0.92, respectively).

conclusionsThe use of antiperspirant/deodorant during breast RT does not significantly affect the incidence of acute RD, pruritus, and pain. As such, the current evidence does not support recommendation against antiperspirant/deodorant use during RT.

Indexed as

Breast NeoplasmsDeodorantsDermatitisAntiperspirantsFemaleHumansPainPruritusAntiperspirantsDeodorantsAntiperspirantBreast cancerDeodorantRadiotherapySkin care

Identifiers

PMID36867303
OpenAlexW4323036954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.