Evidence map›Paper›PMID 36867261›Full record

ArticleLangenbeck's archives of surgery2023

The role of adjuvant pharmacotherapy with liraglutide for patients with inadequate weight loss following bariatric surgery.

James R M Colbourne, Oliver M Fisher, Shirley Mo, Georgia S Rigas, Michael L Talbot

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 7 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 7 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

James R M ColbourneUpper GI Surgery Unit, St George Hospital, Sydney, Australia. j.rmcolbourne@gmail.com.
Oliver M FisherUpper GI Surgery Unit, St George Hospital, Sydney, Australia.
Shirley MoUpper GI Surgery Unit, St George Hospital, Sydney, Australia.
Georgia S RigasUpper GI Surgery Unit, St George Hospital, Sydney, Australia.
Michael L TalbotUpper GI Surgery Unit, St George Hospital, Sydney, Australia.
St George Hospital · AUSutherland Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDespite the benefits of bariatric surgery for many patients, there are a proportion of patients who do not achieve adequate weight loss. We evaluate the role of liraglutide as adjuvant pharmacotherapy in those who respond poorly to weight loss surgery. MATERIALS AND

methodsA non-controlled, prospective, open-label cohort study in which participants are prescribed liraglutide following inadequate response to weight loss surgery. The efficacy and tolerability of liraglutide was measured through measurement of BMI and monitoring of side effect profile.

resultsA total of 68 partial responders to bariatric surgery were included in the study, 2 participants were lost to follow-up. Overall 89.7% lost weight on liraglutide, with 22.1% showing a good response (>10% total body weight loss). There were 41 patients who discontinued liraglutide mainly due to cost.

conclusionLiraglutide is efficacious in achieving weight loss and reasonably well tolerated in patients who have inadequate weight loss post-bariatric surgery.

Indexed as

Bariatric SurgeryLiraglutideChemotherapy, AdjuvantCohort StudiesHumansProspective StudiesLiraglutideBariatric surgeryInadequate weight lossLiraglutide

Identifiers

PMID36867261
PMCPMC9984502
OpenAlexW4323035907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.