SynthesisEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2023
Characterizing recurrent infections after one-stage revision for periprosthetic joint infection of the knee: a systematic review of the literature.
Synthesis in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Detection of Prosthetic Loosening in Hip and Knee Arthroplasty Using Machine Learning: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Use of a Bioresorbable Antibacterial Coating (DACAntibiotics (Basel, Switzerland) · 2026Article
- Modulating Micrococcal Nuclease-Triggered Antibiotic Releases for One-Stage Revisions ofACS infectious diseases · 2026Article
- Fluoroquinolones vs. tetracycline agents combined with rifampicin for periprosthetic joint infections: a comparative study.Journal of bone and joint infection · 2026Article
- Gastrocnemius Flap Reconstruction in Single-Stage Re-Revision Total Knee Arthroplasty for Infection with Soft-Tissue Defects: A Limb Salvage Approach.The American journal of case reports · 2025Article
- Comparison of synovial calprotectin and alpha-defensin for the diagnosis of persistent periprosthetic joint infections at second stage of a two-stage revision arthroplasty.Archives of orthopaedic and trauma surgery · 2025Article
- Animal Models of Orthopedic Implant-Associated Infections and Revisions.ACS biomaterials science & engineering · 2025Review
- Two-stage total joint replacement for hip or knee septic arthritis: post-traumatic etiology and difficult-to-treat infections predict poor outcomes.Archives of orthopaedic and trauma surgery · 2024Article
- Early and delayed periprosthetic joint infection in robot-assisted total knee arthroplasty: a multicenter study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Dalbavancin as suppressive therapy for implant-related infections: a case series with therapeutic drug monitoring and review of the literature.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Review
- Nanoparticle ultrasonication outperforms conventional irrigation solutions in eradicating Staphylococcus aureus biofilm from titanium surfaces: an in vitro study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Clinical use and applications of a citrate-based antiseptic lavage for the prevention and treatment of PJI.Frontiers in medicine · 2024Article
- Two-stage revision in periprosthetic joint infection of the hip using a new intraoperatively molded articulating spacer design.Journal of clinical orthopaedics and trauma · 2023Article
- Outcomes of modular stem for the treatment of periprosthetic femoral fracture: a systematic review of the literature.Annals of joint · 2023Review
- Trabecular titanium cups in hip revision surgery: a systematic review of the literature.Annals of joint · 2023Review
- A Rare Case of Open (Gustilo II) Periprosthetic Fracture (Vancouver B2) in a Polytraumatized Patient.The archives of bone and joint surgery · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriprosthetic joint infection (PJI) of the knee represents a severe complication after 1.5% to 2% of primary total knee replacement. Although two-stage revision was considered the gold-standard treatment for PJI of the knee, in the last decades, more studies reported the outcomes of one-stage revisions. This systematic review aims to assess reinfection rate, infection-free survival after reoperation for recurrent infection, and the microorganisms involved in both primary and recurrent infection. MATERIAL AND
methodsA systematic review of all studies reporting the outcome of one-stage revision for PJI of the knee up to September 2022, according to PRISMA criteria and AMSTAR2 guidelines, was performed. Patient demographics, clinical, surgical, and postoperative data were recorded. PROSPERO ID: CRD42022362767.
resultsEighteen studies with a total of 881 one-stage revisions for PJI of the knee were analyzed. A reinfection rate of 12.2% after an average follow-up of 57.6 months was reported. The most frequent causative microorganism were gram-positive bacteria (71.1%), gram-negative bacteria (7.1%), and polymicrobial infections (8%). The average postoperative knee society score was 81.5, and the average postoperative knee function score was 74.2. The infection-free survival after treatment for recurrent infection was 92.1%. The causative microorganisms at reinfections differed significantly from the primary infection (gram-positive 44.4%, gram-negative 11.1%).
conclusionPatients who underwent a one-stage revision for PJI of the knee showed a reinfection rate lower or comparable to other surgical treatments as two-stage or DAIR (debridement, antibiotics, and implant retention). Reoperation for reinfection demonstrates a lower success compared to one-stage revision. Moreover, microbiology differs between primary infection and recurrent infection. Level of evidence Level IV.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.