Evidence map›Paper›PMID 36867221›Full record

ArticleArchives of dermatological research2023

Symptoms of attention deficit hyperactivity disorder are associated with Hidradenitis suppurativa in Danish blood donors.

Pernille Lindsø Andersen, Bente Villumsen, Ditte Marie Lindhardt Saunte, Kristoffer Sølvsten Burgdorf, Maria Didriksen, Sisse Rye Ostrowski, Lise Wegner Thørner, Christian Erikstrup, Khoa Manh Dinh, Kaspar René Nielsen and 6 more

Abstract read
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In one paragraph

Article in Archives of dermatological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 2 countries.

Pernille Lindsø Andersen *Department of Dermatology, Zealand University Hospital Roskilde, Sygehusvej 5, 4000, Roskilde, Denmark. pehso@regionsjaelland.dk.ORCID http://orcid.org/0000-0002-0132-4715
Bente Villumsen *The HS Patients' Association, Copenhagen, Denmark.
Ditte Marie Lindhardt SaunteDepartment of Dermatology, Zealand University Hospital Roskilde, Sygehusvej 5, 4000, Roskilde, Denmark.ORCID http://orcid.org/0000-0001-7953-1047
Kristoffer Sølvsten BurgdorfDepartment of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-5814-6844
Maria DidriksenDepartment of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-4856-496X
Sisse Rye OstrowskiDepartment of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-5288-3851
Lise Wegner ThørnerDepartment of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Christian ErikstrupDepartment of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.ORCID http://orcid.org/0000-0001-6551-6647
Khoa Manh DinhDepartment of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.ORCID http://orcid.org/0000-0003-1881-5673
Kaspar René NielsenDepartment of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark.
Thorsten BrodersenDepartment of Clinical Immunology, Zealand University Hospital, Køge, Denmark.ORCID http://orcid.org/0000-0003-4431-9972
Mie Topholm BruunDeparment of Clinical Immunology, Odense University Hospital, Odense, Denmark.
Karina BanasikThe Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Thomas Folkmann HansenThe Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-6703-7762
Ole Birger Pedersen *Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark.ORCID http://orcid.org/0000-0003-2312-5976
Gregor Borut Jemec *Department of Dermatology, Zealand University Hospital Roskilde, Sygehusvej 5, 4000, Roskilde, Denmark.ORCID http://orcid.org/0000-0002-0712-2540
University of Copenhagen · DKCopenhagen University Hospital · DKAarhus University Hospital · DKAalborg University Hospital · DKOdense University Hospital · DKRoskilde Sygehus · DKThe Patients Association · GBZealand University Hospital Køge · DK

Funding

LEO Fondet LF18002
6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with psychiatric comorbidity. Attention deficit hyperactivity disorder (ADHD) is a mental disorder associated with systemic and skin inflammation such as psoriasis and atopic dermatitis. Whether HS symptoms are associated with ADHD symptoms remains unexplored. Thus, the aim of this study was to explore the possible association between HS and ADHD. Participants in the Danish Blood Donor Study (DBDS) were included in this cross-sectional study during 2015-2017. The participants provided questionnaire data on screening items of HS, ADHD symptoms (ASRS-score), and depressive symptoms, smoking and body mass index (BMI). A logistic regression with HS symptoms as a binary outcome predicted by ADHD adjusted for age, sex, smoking, BMI, and depression was conducted to investigate the association between HS and ADHD. A total of 52,909 Danish blood donors were included in the study. Of these were 1004/52,909 (1.9%) considered participants with HS. Of the participants with HS, 74/996 (7.4%) screened positive of ADHD symptoms, while only 1786/51,129 (3.5%) of the participants without HS screened positive of ADHD. Adjusted for confounders, ADHD was positively associated with HS, odds ratio 1.85 (95% confidence interval: 1.43-2.37). Psychiatric comorbidity of HS is not limited to depression and anxiety. This study shows a positive association between HS and ADHD. Further research on the biological mechanisms behind this association is warranted.

Indexed as

Acne inversaADHDEpidemiologyHidradenitis suppurativaPsychiatry

Identifiers

PMID36867221
OpenAlexW4323037470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.