Evidence map›Paper›PMID 36866691›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Mammographic Density Reduction is Associated to the Prognosis in Asian Breast Cancer Patients Receiving Hormone Therapy.

Wei-Chung Shia, Li-Sheng Lin, Hwa-Koon Wu, Chih-Jung Chen, Dar-Ren Chen

Abstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei-Chung ShiaMolecular Medicine Laboratory, Department of Research, Changhua Christian Hospital, Changhua, Taiwan.ORCID 0000-0001-5351-840X
Li-Sheng LinDepartment of Breast Surgery, 117821The Affiliated Hospital (Group) of Putian University, Putian, Fujian, China.
Hwa-Koon WuDepartment of Medical Imaging, Changhua Christian Hospital, Changhua, Taiwan.
Chih-Jung ChenDepartment of Pathology and Laboratory Medicine, 40293Taichung Veterans General Hospital, Taichung, Taiwan.
Dar-Ren ChenDepartment of General Surgery, Changhua Christian Hospital, Changhua, Taiwan.ORCID 0000-0002-0897-4374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUsing mammographic density as a significant biomarker for predicting prognosis in adjuvant hormone therapy patients is controversial due to the conflicting results of recent studies. This study aimed to evaluate hormone therapy-induced mammographic density reduction and its association with prognosis in Taiwanese patients

methodsIn this retrospective study, 1941 patients with breast cancer were screened, and 399 patients with estrogen receptor

resultsA mammographic density reduction rate >20.8%, measured preoperatively and after receiving hormone therapy from 12-18 months, was a significant threshold for predicting prognosis in patients with breast cancer. The disease-free survival rate was significantly higher in patients whose mammographic density reduction rate was >20.8% (P = .048).

conclusionThis study's findings could help estimate the prognosis for patients with breast cancer and may improve the quality of adjuvant hormone therapy after enlarging the study cohort in the future.

Indexed as

Breast NeoplasmsBreast DensityFemaleHumansNeoplasm Recurrence, LocalPrognosisRetrospective Studiesaromatase inhibitorbreast cancerbreast densityestrogen receptortamoxifen

Identifiers

PMID36866691
PMCPMC9989438

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