Evidence map›Paper›PMID 36866590›Full record

ArticleStatistics in medicine2023

Confidence intervals for prevalence estimates from complex surveys with imperfect assays.

Damon M Bayer, Michael P Fay, Barry I Graubard

Abstract read
In one paragraph

Article in Statistics in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Estimating SARS-CoV-2 seroprevalence.Journal of the Royal Statistical Society. Series A, (Statistics in Society) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Damon M BayerBiostatistics Research Branch, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.ORCID 0000-0003-2819-7645
Michael P FayBiostatistics Research Branch, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.ORCID 0000-0002-8643-9625
Barry I GraubardDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA.ORCID 0000-0002-6787-1105
National Cancer Institute · USNational Institute of Allergy and Infectious Diseases · USUniversity of California, Irvine · US

Funding

Consultation and CollaborationZIACP010184 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI GRAUBARD, BARRY · 2010 to 2020
$16.3M
Intramural NIH HHS ZIA CP010184
6 · The paper itself

Abstract

There are established methods for estimating disease prevalence with associated confidence intervals for complex surveys with perfect assays, or simple random sample surveys with imperfect assays. We develop and study methods for the complicated case of complex surveys with imperfect assays. The new methods use the melding method to combine gamma intervals for directly standardized rates and established adjustments for imperfect assays by estimating sensitivity and specificity. One of the new methods appears to have at least nominal coverage in all simulated scenarios. We compare our new methods to established methods in special cases (complex surveys with perfect assays or simple surveys with imperfect assays). In some simulations, our methods appear to guarantee coverage, while competing methods have much lower than nominal coverage, especially when overall prevalence is very low. In other settings, our methods are shown to have higher than nominal coverage. We apply our method to a seroprevalence survey of SARS-CoV-2 in undiagnosed adults in the United States between May and July 2020.

Indexed as

COVID-19SARS-CoV-2AdultConfidence IntervalsHumansPrevalenceSeroepidemiologic Studiesconfidence distributionsmelding confidence intervalsseroprevalencesurvey samplingweighted sampling

Identifiers

PMID36866590
PMCPMC11949243
OpenAlexW4323037464

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.