ArticleFrontiers in neuroscience2023
Efficacy of acupuncture for the treatment of Parkinson's disease-related constipation (PDC): A randomized controlled trial.
Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Acupuncture-related therapies for opioid-induced constipation in patients with cancer: a systematic review and network meta-analysis.Frontiers in medicine · 2026Pooled it
- Efficacy of various acupuncture modalities on alleviating symptoms in Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Comparative efficacy of non-pharmacological interventions for Parkinson's disease with constipation: a systematic review and network meta-analysis.Frontiers in neurology · 2025Pooled it
- Fire Needling Therapy versus Usual Care for Parkinson's Disease-Related Chronic Pain: A Pilot Randomized Controlled Trial.Journal of pain research · 2024Trial
- Efficacy of Acupuncture for Pain in Parkinson's Disease: Study Protocol for a Randomized Controlled Trial.Journal of pain research · 2026Article
- Efficacy of acupuncture for patients with Parkinson's disease-related constipation: study protocol for a randomized controlled, double-blind trial.Frontiers in neuroscience · 2026Article
- Progress in diagnosis and treatment of Parkinson's disease and clinical application and prospect of acupuncture and moxibustion treatment.Frontiers in medicine · 2026Review
- Acupuncture for neurodegenerative diseases: mechanisms, efficacy, and future research directions.American journal of translational research · 2025Review
- Efficacy of Acupuncture Therapy in Treating Non-Motor Symptoms of Parkinson's Disease: A Systematic Review and Network Meta-Analysis.Neuropsychiatric disease and treatment · 2025Review
- Efficacy of acupuncture for Parkinson's disease with mild cognitive impairment: study protocol for a randomized controlled trial.Frontiers in neurology · 2025Article
- Analysis of patellar reflex in Parkinson disease patients after an acupuncture treatment protocol - Case series study.Clinical parkinsonism & related disorders · 2025Article
- Acupuncture modulates the microbiota-gut-brain axis: a new strategy for Parkinson's disease treatment.Frontiers in aging neuroscience · 2025Review
- Acupuncture for Parkinson's Disease: A Narrative Review of Clinical Efficacy and Mechanistic Insights.Neuropsychiatric disease and treatment · 2025Review
- Acupuncture Effect on Reaction-Time Changes in Parkinson's Disease Patients-Case Study Series.Journal of clinical medicine · 2024Article
- Acupuncture for Parkinson's disease-related constipation: current evidence and perspectives.Frontiers in neurology · 2023Article
- Acupuncture therapy for Parkinson's disease: a case report demonstrating symptomatic improvement without medication.Frontiers in neurology · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the efficacy of acupuncture in treating Parkinson's disease-related constipation (PDC). Materials and methods: This was a randomized, controlled trial in which patients, outcome assessors, and statisticians were all blinded. Seventy-eight eligible patients were randomly assigned to either the manual acupuncture (MA) or sham acupuncture (SA) groups and received 12 sessions of treatment over a 4-week period. Following treatment, patients were monitored until the eighth week. The primary outcome was the change in weekly complete spontaneous bowel movements (CSBMs) from baseline after treatment and follow-up. The Constipation Symptom and Efficacy Assessment Scale (CSEAS), the Patient-Assessment of Constipation Quality of Life questionnaire (PAC-QOL), and the Unified Parkinson's Disease Rating Scale (UPDRS) were used as secondary outcomes. Results: In the intention-to-treat analysis, 78 patients with PDC were included, with 71 completing the 4-week intervention and 4-week follow-up. When compared to the SA group, weekly CSBMs were significantly increased after treatment with the MA group ( Conclusion: Acupuncture was found to be effective and safe in treating PDC in this study, and the treatment effect lasted up to 4 weeks. Clinical trial registration: http://www.chictr.org.cn/index.aspx, identifier ChiCTR2200059979.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.