Evidence map›Paper›PMID 36866324›Full record

Article3 Biotech2023

Genome-wide association study revealed suggestive QTLs for production and reproduction traits in Indian Murrah buffalo.

D Ravi Kumar, P B Nandhini, M Joel Devadasan, Jayakumar Sivalingam, Destaw Worku Mengistu, Archana Verma, I D Gupta, S K Niranjan, R S Kataria, M S Tantia

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In one paragraph

Article in 3 Biotech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

D Ravi KumarICAR-National Dairy Research Institute, Karnal, Haryana India.
P B NandhiniICAR-National Dairy Research Institute, Karnal, Haryana India.
M Joel DevadasanICAR-National Dairy Research Institute, Karnal, Haryana India.
Jayakumar SivalingamICAR-National Bureau of Animal Genetic Resources, Karnal, Haryana India.ORCID 0000-0002-0042-6859
Destaw Worku MengistuICAR-National Dairy Research Institute, Karnal, Haryana India.
Archana VermaICAR-National Dairy Research Institute, Karnal, Haryana India.
I D GuptaICAR-National Dairy Research Institute, Karnal, Haryana India.
S K NiranjanICAR-National Bureau of Animal Genetic Resources, Karnal, Haryana India.
R S KatariaICAR-National Bureau of Animal Genetic Resources, Karnal, Haryana India.
M S TantiaICAR-National Bureau of Animal Genetic Resources, Karnal, Haryana India.
National Dairy Research Institute · INNational Bureau of Animal Genetic Resources · INDirectorate of Poultry Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was aimed to identify the genome-wide SNPs associated with production and reproduction traits in 96 Indian Murrah buffalo genotyped based on ddRAD approach using Genome-Wide Association Study (GWAS) along with phenotypes of contemporary animals using mixed linear model for production and reproduction traits. A total of 27,735 SNPs identified using ddRAD approach in 96 Indian Murrah buffaloes were used for GWAS. A total of 28 SNPs were found to be associated with production and reproductive traits. Among these, 14 SNPs were present in the intronic region of AK5, BACH2, DIRC2, ECPAS, MPZL1, MYO16, QRFPR, RASGRF1, SLC9A4, TANC1, and TRIM67 genes and one SNP in long non-coding region of LOC102414911. Out of these 28 SNPs, 9 SNPs were found to have pleiotropic effect over milk production traits and were present in chromosome number BBU 1, 2, 4, 6, 9, 10, 12, 19, and 20. SNPs in the intronic region of AK5, TRIM67 genes were found to be associated with milk production traits. Eleven and five SNPs in the intergenic region were associated with milk production and reproduction traits respectively. The above genomic information may be used for selection of Murrah animals for genetic improvement.

Indexed as

BuffaloddRADGWASQTLsSNP

Identifiers

PMID36866324
PMCPMC9971368
OpenAlexW4322495063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.