ArticleToxicology research2023
Prognostic factors in acute poisoning with central nervous system xenobiotics: development of a nomogram predicting risk of intensive care unit admission.
Article in Toxicology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 19 citations in OpenAlex.
- Explainable artificial intelligence in ICU admission prediction for methanol poisoning patients: a comparative study of deep and machine learning models.International journal of emergency medicine · 2026Article
- Construction and validation of a prognostic nomogram for predicting in-hospital mortality of patients with acute chlorfenapyr poisoning.American journal of translational research · 2026Article
- Prediction of QTc Prolongation in Acute Poisoning with Atypical Antipsychotics Using Machine Learning Techniques: A Study from Poison Control Center.Cardiovascular toxicology · 2025Article
- Development and validation of a prognostic nomogram for predicting of patients with acute sedative-hypnotic overdose admitted to the intensive care unit.Scientific reports · 2025Article
- Acute Intoxications Admitted to the Intensive Care Unit: A Retrospective Cohort Study.Journal of toxicology · 2025Article
- Assessment of co-ingestion effects on poisoning patterns, drug-drug interactions, and adverse outcomes in acute toxic exposure.Toxicology reports · 2024Article
- Prognostic value of PGI score compared to poison severity score (PSS) and simplified acute physiology score (SAPS) II as predictors of mortality and other adverse outcomes in acute poisoning with aluminum phosphide.Toxicology reports · 2024Article
- Outcome assessment of acute methanol poisoning: A risk-prediction nomogram approach for in-hospital mortality.Toxicology reports · 2024Article
- Predictors of Serotonin Syndrome in Acute Poisoning with 5-Hydroxytryptamine Modulators.Toxics · 2024Article
- Performance of several clinical scoring systems as predictors of adverse outcomes in acute exposure to toxic alcohols.Toxicology research · 2024Article
- Clinical prediction models for intensive care unit admission in patients with acute poisoning: is it time for a comprehensive evaluation of their utility?Toxicology research · 2024Article
- A nomogram proposal for early prediction of intensive care unit admission in patients with acute antipsychotic poisoning.Toxicology research · 2023Article
- Evaluation of various scoring systems as predictors of the need for intensive care unit admission and other adverse outcomes among patients with acute clozapine poisoning.Toxicology research · 2023Article
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acute intoxication with central nervous system (CNS) xenobiotics is an increasing global problem. Predicting the prognosis of acute toxic exposure among patients can significantly alter the morbidity and mortality. The present study outlined the early risk predictors among patients diagnosed with acute exposure to CNS xenobiotics and endorsed bedside nomograms for identifying patients requiring intensive care unit (ICU) admission and those at risk of poor prognosis or death. Methods: This study is a 6-year retrospective cohort study conducted among patients presented with acute exposure to CNS xenobiotics. Results: A total of 143 patients' records were included, where (36.4%) were admitted to the ICU, and a significant proportion of which was due to exposure to alcohols, sedative hypnotics, psychotropic, and antidepressants ( Conclusion: The proposed nomograms yielded significant straightforward and reliable prognostic outcomes predictors in acute exposure to CNS xenobiotics.
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