Evidence map›Paper›PMID 36865993›Full record

ArticleIJID regions2023

Etiology, clinical characteristics, and risk factors associated with severe influenza-like illnesses in Mexican adults.

Paola Del Carmen Guerra-de-Blas, Ana M Ortega-Villa, Ana A Ortiz-Hernández, Alejandra Ramírez-Venegas, Sarbelio Moreno-Espinosa, Beatriz Llamosas-Gallardo, Santiago Pérez-Patrigeon, Sally Hunsberger, Martín Magaña, Rafael Valdez-Vázquez and 8 more

Open access · goldAbstract read
In one paragraph

Article in IJID regions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 2 countries.

Paola Del Carmen Guerra-de-BlasThe Mexican Emerging Infectious Diseases Clinical Research Network (LaRed), Mexico City, Mexico.
Ana M Ortega-VillaNational Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Ana A Ortiz-HernándezInstituto Nacional de Pediatría, Mexico City, Mexico.
Alejandra Ramírez-VenegasInstituto Nacional de Enfermedades Respiratorias "Ismael Cosío Villegas", Mexico City, Mexico.
Sarbelio Moreno-EspinosaHospital Infantil de México Federico Gómez, Instituto Nacional de Salud, Mexico City, Mexico.
Beatriz Llamosas-GallardoInstituto Nacional de Pediatría, Mexico City, Mexico.
Santiago Pérez-PatrigeonInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Sally HunsbergerNational Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Martín MagañaHospital Regional Dr. Ignacio Morones Prieto, San Luis Potosí, Mexico.
Rafael Valdez-VázquezHospital General "Dr. Manuel Gea González", Mexico City, Mexico.
Laura FreimanisWestat, Rockville, Maryland, USA.
Juan Francisco Galán-HerreraThe Mexican Emerging Infectious Diseases Clinical Research Network (LaRed), Mexico City, Mexico.
M Lourdes Guerrero-AlmeidaInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
John H PowersClinical Research Directorate, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Guillermo M Ruiz-PalaciosInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
John BeigelNational Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Arturo Galindo-FragaInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Mexican Emerging Infectious Diseases Clinical Research Networka
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXNational Institute of Allergy and Infectious Diseases · USInstituto Nacional de Pediatria · MXFrederick National Laboratory for Cancer Research · USHospital Central Dr. Ignacio Morones Prieto · MXHospital General Dr. Manuel Gea Gonzalez · MXHospital Infantil de México Federico Gómez · MXInstituto Nacional de Enfermedades Respiratorias · MXInstituto Politécnico Nacional · MXWestat (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to determine the risk factors associated with severe influenza-like illness (ILI) in Mexican adults that could be useful to clinicians when assessing patients with ILI. Methods: Data from adult patients enrolled from 2010 through 2014 in ILI002 - a prospective hospital-based observational cohort study - were analyzed. Etiology and clinical characteristics were compared between cases of severe ILI (defined as hospitalization and/or death) and cases of non-severe ILI. Results: Overall, 1428 (39.0%) out of a total 3664 cases of ILI were classified as severe. Adjusted analyses showed a higher risk of severe ILI associated with signs and symptoms related to lower tract infection, i.e. cough with sputum (odds ratio (OR) 2.037, 95% confidence interval (CI) 1.206-3.477; Conclusions: Respiratory viruses can cause severe ILI. The results of this study highlight the importance of evaluating data compatible with lower tract involvement and previous use of immunosuppressants at baseline, because patients meeting these conditions may develop severe illness.

Indexed as

AdultsDisease severityInfluenzaRisk factors

Identifiers

PMID36865993
PMCPMC9972394
OpenAlexW4318827521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.