Evidence map›Paper›PMID 36865786›Full record

ArticleJournal of multidisciplinary healthcare2023

Multidisciplinary Team (MDT) Discussion Improves Overall Survival Outcomes for Metastatic Renal Cell Carcinoma Patients.

Yuhao Zeng, Sha Zhu, Zilin Wang, Junru Chen, Jindong Dai, Zhenhua Liu, Guangxi Sun, Jiayu Liang, Xingming Zhang, Zhipeng Wang and 16 more

Abstract read
In one paragraph

Article in Journal of multidisciplinary healthcare, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Association of multidisciplinary team management with survival in sinonasal malignancies: a real-world IPTW cohort study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  6. Wellbeing status and priority concerns of patients with advanced renal cell carcinoma: results of the EONS PROMs project international online survey.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  7. Article
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  9. [Clinical application of multidisciplinary team in the diagnosis and treatment of chronic refractory wounds].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Article
  10. Immunotherapy in Renal Cell Carcinoma.Cancer treatment and research · 2025
    Review
  11. Article
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  15. The Role of Surgery in Metastatic Renal Cell Carcinoma in 2024.Clinical Medicine Insights. Oncology · 2024
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Yuhao Zeng *Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Sha Zhu *Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Zilin WangDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Junru ChenDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Jindong DaiDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Zhenhua LiuDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Guangxi SunDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Jiayu LiangDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Xingming ZhangDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Zhipeng WangDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Jinge ZhaoDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0002-2790-462X
Yuchao NiDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Jiyu YangDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Minghao WangDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Qiang WeiDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Xiang LiDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0001-8471-0015
Ni ChenDepartment of Pathology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Zhiping LiDepartment of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Xin WangDepartment of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Yali ShenDepartment of Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Jin YaoDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Rui HuangDepartment of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Jiyan LiuDepartment of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0003-4885-5481
Diming CaiDepartment of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Hao ZengDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0002-1267-0509
Pengfei ShenDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.ORCID 0000-0002-0370-0411

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Multidisciplinary team (MDT) discussion is a widely used model to manage patients diagnosed with cancer. However, there has been no direct evidence to prove its effect on the prognosis of metastatic renal cell carcinoma (mRCC) patients, so this study explored the impact of MDT discussion on mRCC patient survival. Methods: The clinical data of 269 mRCC patients were retrospectively collected from 2012 to 2021. The cases were grouped into the MDT and non-MDT groups, then subgroup analysis was performed according to different histology types, as well as exploring the role of MDT in patients who have undergone multiple-line therapy. Overall survival (OS) and progression free survival (PFS) were set as the study endpoint. Results: Approximately half (48.0%, 129/269) of the patients were in the MDT group, with univariable survival analyses showing these patients had remarkably longer median OS (MDT group: 73.7 months; non-MDT group: 33.2 months, hazard ratio (HR): 0.423 (0.288, 0.622), p<0.001) and longer median PFS (MDT group: 16.9 months, non-MDT group: 12.7 months, HR: 0.722 (0.542, 0.962), p=0.026). Furthermore, MDT management resulted in longer survival for both ccRCC and non-ccRCC subgroups. Patients in the MDT group were more likely to receive multi-line therapy (MDT group: 79/129, 61.2% vs non-MDT group: 56/140, 40.0%, p<0.001), and within this patient group, MDT management still resulted in longer OS (MDT group: 94.0 months; non-MDT group: 43.5 months, p=0.009). Conclusion: MDT is associated with prolonged overall survival in mRCC independent of histology, ensuring that patients receive better management and precise treatment.

Indexed as

ccRCCMDTmRCCmulti-line treatmentnon-ccRCCoverall survivalprognosis

Identifiers

PMID36865786
PMCPMC9971520

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.