ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2023
Decreased hospital readmissions after programmatic strengthening of an outpatient parenteral antimicrobial therapy (OPAT) program.
Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Safety and Efficacy of Outpatient Parenteral Antibiotic Therapy (OPAT) in Patients With Infective Endocarditis: A Systematic Review and Meta-Analysis.Clinical cardiology · 2025Pooled it
- Clinical Experience with Omadacycline for the Treatment of Diabetic Foot Infections and Acute Osteomyelitis.Infectious diseases and therapy · 2026Article
- Outpatient Parenteral Antimicrobial Therapy Practice Variability Across Veterans Affairs Hospitals.JAMA network open · 2026Article
- Clinical Outcomes and Safety Profile of Vancomycin in Outpatient Parenteral Antimicrobial Therapy Services: A Systematic Review.Antibiotics (Basel, Switzerland) · 2026Review
- Challenges and drivers in the implementation of current practices in outpatient parenteral antimicrobial therapy: an international survey.JAC-antimicrobial resistance · 2026Article
- 2026 Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK.JAC-antimicrobial resistance · 2026Review
- Emphasizing the O in OPAT: A Pathway for Clinic-Initiated Outpatient Parenteral Antimicrobial Therapy (CI-OPAT) at an Academic Center.Open forum infectious diseases · 2026Article
- Improving hospital-based care for patients with injection-drug related infections: provider perspectives.Addiction science & clinical practice · 2026Article
- Continuous infusion OPAT via elastomeric pumps: effectiveness, safety, and cost-saving potential in a real-world Italian cohort.Infection · 2026Article
- Outpatient parenteral antimicrobial therapy delivery, readmission rates, and multidisciplinary teams: a scoping review of the impact of published quality indicators.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Cost avoidance analysis of outpatient parenteral antimicrobial therapy (OPAT) plan reconciliation for patients enrolled in value-based payment models at an academic hospital.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Outpatient Parenteral Antimicrobial Therapy in a Tertiary Hospital in France: A Description of Service Models and Costs.Antibiotics (Basel, Switzerland) · 2025Article
- Risk Factors for Hospital Readmission Following Outpatient Parenteral Antimicrobial Therapy (OPAT).Infectious diseases and therapy · 2025Article
- Inpatient Cost Avoidance and Uncompensated Labor Associated With Different Outpatient Parenteral Antimicrobial Therapy Care Models.Open forum infectious diseases · 2025Article
- Quantifying cost savings from outpatient parenteral antimicrobial therapy programme: a systematic review and meta-analysis.JAC-antimicrobial resistance · 2025Review
- Outcome of outpatient parenteral antibiotic therapy (OPAT) program at a tertiary care hospital in India.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- A Bundle of the "Top 10" Outpatient Parenteral Antimicrobial Therapy Publications in 2023.Open forum infectious diseases · 2024Review
- Current practices and challenges of outpatient parenteral antimicrobial therapy: a narrative review.The Journal of antimicrobial chemotherapy · 2024Review
- Outpatient parenteral antimicrobial therapy (OPAT) across the world: a comparative analysis-what lessons can we learn?JAC-antimicrobial resistance · 2024Review
- Improving antimicrobial treatment in terms of antimicrobial stewardship and health costs by an OPAT service.Infection · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To determine whether a structured OPAT program supervised by an infectious disease physician and led by an OPAT nurse decreased hospital readmission rates and OPAT-related complications and whether it affected clinical cure. We also evaluated predictors of readmission while receiving OPAT. Patients: A convenience sample of 428 patients admitted to a tertiary-care hospital in Chicago, Illinois, with infections requiring intravenous antibiotic therapy after hospital discharge. Methods: In this retrospective, quasi-experimental study, we compared patients discharged on intravenous antimicrobials from an OPAT program before and after implementation of a structured ID physician and nurse-led OPAT program. The preintervention group consisted of patients discharged on OPAT managed by individual physicians without central program oversight or nurse care coordination. All-cause and OPAT-related readmissions were compared using the χ Results: In total, 428 patients were included in the study. Unplanned OPAT-related hospital readmissions decreased significantly after implementation of the structured OPAT program (17.8% vs 7%; Conclusion: A structured ID physician and nurse-led OPAT program was associated with a decrease in OPAT-related readmissions and improved clinical cure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.