Evidence map›Paper›PMID 36865553›Full record

ArticleFrontiers in immunology2023

The IgH

Ophélie A Martin, Morgane Thomas, Marie Marquet, Charlotte Bruzeau, Armand Garot, Mylène Brousse, Sébastien Bender, Claire Carrion, Jee Eun Choi, Bao Q Vuong and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Ophélie A MartinLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Morgane ThomasLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Marie MarquetLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Charlotte BruzeauLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Armand GarotLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Mylène BrousseLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Sébastien BenderLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Claire CarrionLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Jee Eun ChoiThe Graduate Center, The City University of New York, New York, NY, United States.
Bao Q VuongThe Graduate Center, The City University of New York, New York, NY, United States.
Patricia J GearhartLaboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States.
Robert W MaulLaboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States.
Sandrine Le NoirLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Eric PinaudLaboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.
Centre National de la Recherche Scientifique · FRInserm · FRNational Institutes of Health · USUniversité de Limoges · FRCity University of New York · USThe Graduate Center, CUNY · US

Funding

Roles for Transcription in Antibody DiversityZIAAG000714 · NIA · NATIONAL INSTITUTE ON AGING · PI GEARHART, PATRICIA J · 2009 to 2025
$10.9M
6 · The paper itself

Abstract

Intoduction: Two scaffold/matrix attachment regions (5'- and 3'- Methods: Our study analyzed SHM and its transcriptional control in a mouse model devoid of Results: We observed an inverted substitution pattern in of Discussion: Our study pointed out an unexpected "fence" function of

Indexed as

DNA Mismatch RepairDNA RepairImmunoglobulin Heavy ChainsSomatic Hypermutation, ImmunoglobulinAnimalsDisease Models, AnimalHumansIntronsMicePhenotypeImmunoglobulin Heavy ChainsB cellimmunoglobulin geneMARs regionsomatic hypermutation (SHM)UNG

Identifiers

PMID36865553
PMCPMC9971809
OpenAlexW4320725731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.