Evidence map›Paper›PMID 36865510›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2023

Incidence, Subtypes, Risk factors, and Outcome of Delirium: A Prospective Observational Study from Indian Intensive Care Unit.

Anand Mohanlal Tiwari, Kapil Gangadhar Zirpe, Afroz Ziyaulla Khan, Sushma Kirtikumar Gurav, Abhijit Manikrao Deshmukh, Prasad Bhimrao Suryawanshi, Upendrakumar S Kapse, Prajkta Prakash Wankhede, Shrirang Nagorao Bamne, Abhaya Pramodrao Bhoyar and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Comparison of Two Doses of Prophylactic Melatonin on Incidence of Delirium in Intensive Care Unit Patients: A Randomized Controlled Trial.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Reliability and Validity of Hindi Version of the Confusion Assessment Method for Intensive Care Unit (CAM-ICU) for Diagnosis of Delirium: A Cohort Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Anand Mohanlal TiwariDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-9791-8365
Kapil Gangadhar ZirpeDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-8140-727X
Afroz Ziyaulla KhanDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0003-3170-496X
Sushma Kirtikumar GuravDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0001-6875-2071
Abhijit Manikrao DeshmukhDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0001-5602-291X
Prasad Bhimrao SuryawanshiDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0001-7306-8434
Upendrakumar S KapseDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-5279-4485
Prajkta Prakash WankhedeDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-3620-3390
Shrirang Nagorao BamneDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0003-1128-4793
Abhaya Pramodrao BhoyarDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-0460-3162
Ria Vishal MalhotraDepartment of Neuro Trauma Unit, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-1026-0274
Santosh M SontakkeDepartment of Neurology, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0002-6528-8573
Pankaj B BoradeDepartment of Psychiatry, Ruby Hall Clinic, Pune, Maharashtra, India.ORCID https://orcid.org/0000-0003-2436-6341
Ruby Hall Clinic · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Delirium is a common, under-recognized, and often fatal condition in critically ill patients, characterized by acute disorder of attention and cognition. The global prevalence varies with a negative impact on outcomes. A paucity of Indian studies exists that have systematically assessed delirium. Objective: A prospective observational study designed to determine the incidence, subtypes, risk factors, complications, and outcome of delirium in Indian intensive care units (ICUs). Patients and methods: Among 1198 adult patients screened during the study period (December 2019-September 2021), 936 patients were included. The confusion assessment method score (CAM-ICU) and Richmond agitation sedation scale (RASS) were used, with additional confirmation of delirium by the psychiatrist/neurophysician. Risk factors and related complications were compared with a control group. Results: Delirium occurred in 22.11% of critically ill patients. The hypoactive subtype was the most common (44.9%). The risk factors recognized were higher age, increased acute physiology and chronic health evaluation (APACHE-II) score, hyperuricemia, raised creatinine, hypoalbuminemia, hyperbilirubinemia, alcoholism, and smoking. Precipitating factors included patients admitted on noncubicle beds, proximity to the nursing station, requiring ventilation, as well as the use of sedatives, steroids, anticonvulsants, and vasopressors. Complications observed in the delirium group were unintentional removal of catheters (35.7%), aspiration (19.8%), need for reintubation (10.6%), decubitus ulcer formation (18.4%), and high mortality (21.3% vs 5%). Conclusion: Delirium is common in Indian ICUs with a potential effect on length of stay and mortality. Identification of incidence, subtype, and risk factors is the first step toward prevention of this important cognitive dysfunction in the ICU. How to cite this article: Tiwari AM, Zirpe KG, Khan AZ, Gurav SK, Deshmukh AM, Suryawanshi PB,

Indexed as

Acute confusional stateComplicationsDeliriumIntensive care unitMortalityMotor subtypes of deliriumRisk factors

Identifiers

PMID36865510
PMCPMC9973060
OpenAlexW4318778076

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.