Perfusable cell-laden micropatterned hydrogels for delivery of spatiotemporal vascular-like cues to tissues.

Walter B Varhue, Aditya Rane, Ramon Castellanos-Sanchez, Shayn M Peirce, George Christ, Nathan S Swami

Abstract read

In one paragraph

Article in Organs-on-a-chip, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Open-Top Patterned Hydrogel-Laden 3D Glioma Cell Cultures for Creation of Dynamic Chemotactic Gradients to Direct Cell Migration.ACS biomaterials science & engineering · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Walter B VarhueElectrical and Computer Engineering, University of Virginia, Charlottesville, VA, 22904, USA.

Aditya RaneChemistry, University of Virginia, Charlottesville, VA, 22904, USA.

Ramon Castellanos-SanchezBiomedical Engineering, University of Virginia, Charlottesville, VA, 22904, USA.

Shayn M PeirceBiomedical Engineering, University of Virginia, Charlottesville, VA, 22904, USA.

George ChristBiomedical Engineering, University of Virginia, Charlottesville, VA, 22904, USA.

Nathan S SwamiElectrical and Computer Engineering, University of Virginia, Charlottesville, VA, 22904, USA.

Funding

Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Jay William FOX · 1987 to 2026

$72.1M

NCI NIH HHS P30 CA044579

6 · The paper itself

Abstract

The integration of vasculature at physiological scales within 3D cultures of cell-laden hydrogels for the delivery of spatiotemporal mass transport, chemical and mechanical cues, is a stepping-stone towards building

Indexed as

3D cell cultureBiofabricationIn vitro vasculature modelsMicrofluidicsOrgan-on-a-Chip

Identifiers

PMID36865345

DOI10.1016/j.ooc.2022.100017

PMCPMC9977322

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.