Evidence map›Paper›PMID 36865321›Full record

ArticlebioRxiv : the preprint server for biology2023

Non-muscle myosin 2 filaments are processive in cells.

Eric A Vitriol, Melissa A Quintanilla, Joseph J Tidei, Lee D Troughton, Abigail Cody, Bruno A Cisterna, Makenzie L Jane, Patrick W Oakes, Jordan R Beach

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Eric A VitriolDepartment of Neuroscience and Regenerative Medicine, Augusta University, Augusta, GA.
Melissa A QuintanillaDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.
Joseph J TideiDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.
Lee D TroughtonDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.
Abigail CodyDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.
Bruno A CisternaDepartment of Neuroscience and Regenerative Medicine, Augusta University, Augusta, GA.
Makenzie L JaneDepartment of Neuroscience and Regenerative Medicine, Augusta University, Augusta, GA.
Patrick W OakesDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.
Jordan R BeachDepartment of Cell and Molecular Physiology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL.

Funding

MECHANISMS OF CONTRACTILE NETWORK ASSEMBLYR35GM138183 · NIGMS · LOYOLA UNIVERSITY CHICAGO · PI Jordan Beach · 2020 to 2026
$2.8M
Deciphering the Mechanisms and Cellular Roles of Monomer-Driven Actin DynamicsR35GM137959 · NIGMS · UNIVERSITY OF FLORIDA · PI VITRIOL, ERIC A · 2020 to 2024
$2.3M
NIGMS NIH HHS R35 GM137959NIGMS NIH HHS R35 GM138183
6 · The paper itself

Abstract

Directed transport of cellular components is often dependent on the processive movements of cytoskeletal motors. Myosin 2 motors predominantly engage actin filaments of opposing orientation to drive contractile events, and are therefore not traditionally viewed as processive. However, recent

Identifiers

PMID36865321
PMCPMC9980172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.