Evidence map›Paper›PMID 36865266›Full record

ArticlebioRxiv : the preprint server for biology2023

The distinctive mechanical and structural signatures of residual force enhancement in myofibers.

Anthony L Hessel, Michel Kuehn, Bradley M Palmer, Devin Nissen, Dhruv Mishra, Venus Joumaa, Johanna Freundt, Weikang Ma, Kiisa C Nishikawa, Thomas Irving and 1 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Anthony L HesselInstitute of Physiology II, University of Muenster; Muenster, Germany.
Michel KuehnInstitute of Physiology II, University of Muenster; Muenster, Germany.
Bradley M PalmerDepartment of Molecular Physiology and Biophysics, University of Vermont; Burlington, VT, 05405-1705, USA.
Devin NissenBioCAT, Department of Biology, Illinois Institute of Technology; Chicago, IL, USA.
Dhruv MishraDepartment of Biological Sciences, University of Northern Arizona; Flagstaff AZ, USA.
Venus JoumaaHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, AB T2N1N4, Canada.
Johanna FreundtInstitute of Physiology II, University of Muenster; Muenster, Germany.
Weikang MaBioCAT, Department of Biology, Illinois Institute of Technology; Chicago, IL, USA.
Kiisa C NishikawaDepartment of Biological Sciences, University of Northern Arizona; Flagstaff AZ, USA.
Thomas IrvingBioCAT, Department of Biology, Illinois Institute of Technology; Chicago, IL, USA.
Wolfgang A LinkeInstitute of Physiology II, University of Muenster; Muenster, Germany.
Augenstern · DEIllinois Institute of Technology · USNorthern Arizona University · USUniversity of Calgary · CAUniversity of Vermont · US

Funding

The Biophysics Collaborative Access Team (User Training and Outreach)P30GM138395 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI THOMAS C IRVING · 2021 to 2026
$16.5M
Time resolved SAXS studies on the RP2/Arl3 complex pp.484-485P41GM103622 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2012 to 2020
$11.9M
NIGMS NIH HHS P30 GM138395NIGMS NIH HHS P41 GM103622
6 · The paper itself

Abstract

In muscle, titin proteins connect myofilaments together and are thought to be critical for contraction, especially during residual force enhancement (RFE) when force is elevated after an active stretch. We investigated titin's function during contraction using small-angle X-ray diffraction to track structural changes before and after 50% titin cleavage and in the RFE-deficient,

Identifiers

PMID36865266
PMCPMC9980001
OpenAlexW4321443822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.