ArticlebioRxiv : the preprint server for biology2024
Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease.
Angel D'Oliviera, Xuhang Dai, Saba Mottaghinia, Sophie Olson, Evan P Geissler, Lucie Etienne, Yingkai Zhang, Jeffrey S Mugridge
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 8 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
8 authors at 3 institutions in 2 countries.
Angel D'OlivieraDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716.
Xuhang DaiDepartment of Chemistry, New York University, New York, NY 10003.
Saba MottaghiniaCIRI (Centre International de Recherche en Infectiologie), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007 Lyon, France.
Sophie OlsonDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716.
Evan P GeisslerDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716.
Lucie EtienneCIRI (Centre International de Recherche en Infectiologie), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007 Lyon, France.ORCID 0000-0002-8585-7534 University of Delaware · USNew York University · USUniversité Claude Bernard Lyon 1 · FR
Funding
X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Vivian Stojanoff · 2019 to 2026
$38.6MThis renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8MComputational modulator design and machine learning to target protein-protein interactionsR35GM127040 · NIGMS · NEW YORK UNIVERSITY · PI Yingkai Zhang · 2018 to 2026
$4.6MChemistry-Biology Interface Predoctoral Training Grant 2024-2029T32GM133395 · NIGMS · UNIVERSITY OF DELAWARE · PI Catherine Leimkuhler Grimes · 2019 to 2026
$3.7MSelectivity and regulation of mRNA demethylation by iron-dependent dioxygenasesR35GM143000 · NIGMS · UNIVERSITY OF DELAWARE · PI MUGRIDGE, JEFFREY SCOTT · 2021 to 2025
$2.1MMacromolecular X-ray Crystallographic Data Collection SystemS10OD026896 · OD · UNIVERSITY OF DELAWARE · PI BAHNSON, BRIAN J · 2020 to 2020
$580kNIGMS NIH HHS P20 GM104316NIGMS NIH HHS P30 GM133893NIGMS NIH HHS R35 GM127040NIGMS NIH HHS R35 GM143000NIGMS NIH HHS T32 GM133395NIH HHS S10 OD026896
6 · The paper itselfAbstract
The SARS-CoV-2 main protease (M Significance Statement: Viral proteases can strategically target human proteins to manipulate host biochemistry during infection. Here, we show that the SARS-CoV-2 main protease (M
Identifiers
PMID36865253
PMCPMC9980103
OpenAlexW4321499065
What OpenQuestion holds
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