Evidence map›Paper›PMID 36865180›Full record

ArticlebioRxiv : the preprint server for biology2023

A portable regulatory RNA array design enables tunable and complex regulation across diverse bacteria.

Baiyang Liu, Christian Cuba Samaniego, Matthew R Bennett, Elisa Franco, James Chappell

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Baiyang LiuGraduate Program in Systems, Synthetic, and Physical Biology, Rice University, Houston, TX, USA.
Christian Cuba SamaniegoDepartment of Mechanical and Aerospace Engineering, Bioengineering, and Molecular Biology Institute, University of California at Los Angeles, CA, USA.
Matthew R BennettDepartment of Biosciences, Rice University, Houston, TX, USA.
Elisa FrancoDepartment of Mechanical and Aerospace Engineering, Bioengineering, and Molecular Biology Institute, University of California at Los Angeles, CA, USA.
James ChappellDepartment of Biosciences, Rice University, Houston, TX, USA.
Rice University · USUniversity of California, Los Angeles · US

Funding

Dynamics and pattern formation in differentiating cellular populationsR01GM144959 · NIGMS · RICE UNIVERSITY · PI BENNETT, MATTHEW R. · 2021 to 2024
$1.2M
NIGMS NIH HHS R01 GM144959
6 · The paper itself

Abstract

A lack of composable and tunable gene regulators has hindered efforts to engineer non-model bacteria and consortia. To address this, we explore the broad-host potential of small transcription activating RNA (STAR) and propose a novel design strategy to achieve tunable gene control. First, we demonstrate that STARs optimized for

Identifiers

PMID36865180
PMCPMC9980294
OpenAlexW4322207762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.