ArticleFrontiers in psychiatry2023
Predictive potential of somatic symptoms for the identification of subthreshold depression and major depressive disorder in primary care settings.
Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 23 citations in OpenAlex.
- Functional connectivity of the nucleus accumbens and the amygdala in offspring of parents with bipolar or major depressive disorder.European archives of psychiatry and clinical neuroscience · 2026Article
- Frequency and correlates of somatic symptoms in patients of depression: a cross-sectional study at PIMS Islamabad.Annals of medicine and surgery (2012) · 2026Article
- Depressive symptoms and cardiometabolic diseases in Chinese middle-aged and older adults: a longitudinal cross-lagged analysis.BMC public health · 2026Article
- Multimodal behavioral phenotyping for depressive-spectrum classification and severity estimation using eye tracking, facial behavior, and transcript-derived language.Frontiers in psychiatry · 2026Article
- Perceived stress and depression in Chinese university students: a parallel mediation analysis examining the roles of insomnia and somatic symptoms.Frontiers in psychology · 2026Article
- Predicting Suicidal Ideation in Community-based Older Adults Using Self-report Questionnaires with Machine Learning.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- Dry Eye Disease and Psychiatric Disorders: Neuroimmune Mechanisms and Therapeutic Perspectives.International journal of molecular sciences · 2025Review
- Trauma exposure as a predictor of general health outcomes and trauma-related beliefs among older adults living in an adverse environment.Aging & mental health · 2025Article
- The relationship between subthreshold anxiety disorder and symptoms and signs of dry eye disease.Scientific reports · 2025Article
- [Actor-Partner Interdependence Model Analysis of the Relationship Between Individual Social Capital and Depressive Symptoms Among Older Couples Across Different Socioeconomic Statuses].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
- Longitudinal association between somatic symptoms and suicidal ideation in adults with major depressive disorder.Frontiers in psychiatry · 2025Article
- Article
- Depression symptoms are associated with demographic characteristics, nutritional status, and social support among young adults in Chile: a latent class analysis.BMC public health · 2024Article
- Unveiling the Interplay Between Depressive Symptoms' Alleviation and Quality of Life Improvement in Major Depressive Disorder: A Network Analysis Based on Longitudinal Data.Neuropsychiatric disease and treatment · 2024Article
- Mental well-being and sleep quality among vocational college students in Sichuan, China during standardized COVID-19 management measures.Frontiers in public health · 2024Article
- Stressors during the prodromal phase of major depressive episode (CHR-D).Frontiers in psychiatry · 2024Article
- Neuro-11: a new questionnaire for the assessment of somatic symptom disorder in general hospitals.General psychiatry · 2023Article
- Article
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Authors and funding
16 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The presence of heterogenous somatic symptoms frequently obscures the recognition of depression in primary care. We aimed to explore the association between somatic symptoms and subthreshold depression (SD) and Major Depressive Disorder (MDD), as well as to determine the predictive potential of somatic symptoms in identifying SD and MDD in primary care. Methods: Data were derived from the Depression Cohort in China study (ChiCTR registry number: 1900022145). The Patient Health Questionnaire-9 (PHQ-9) was used to assess SD by trained general practitioners (GPs), and the Mini International Neuropsychiatric Interview depression module was used to diagnose MDD by professional psychiatrists. Somatic symptoms were assessed using the 28-item Somatic Symptoms Inventory (SSI). Results: In total of 4,139 participants aged 18-64 years recruited from 34 primary health care settings were included. The prevalence of all 28 somatic symptoms increased in a dose-dependent manner from non-depressed controls to SD, and to MDD ( Conclusions: Somatic symptoms were associated with the presence of SD and MDD. In addition, somatic symptoms, notably those related to energy, showed good predictive potential in identifying SD and MDD in primary care. The clinical implication of the present study is that GPs should consider the closely related somatic symptoms for early recognition for depression in practice.
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