ReviewFrontiers in medicine2023
Microvascular dysfunction following cardiopulmonary bypass plays a central role in postoperative organ dysfunction.
Review in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 29 citations in OpenAlex.
- Intraoperative Dexmedetomidine Enhances Postoperative Microcirculation and Reduces Acute Kidney Injury in Cardiac Surgery: A Double-Blind Randomized Trial.Drug design, development and therapy · 2025Trial
- Perioperative Factors Associated with Delayed Extubation After the Ross Procedure for Aortic Regurgitation: A Retrospective Cohort Study.Pediatric cardiology · 2026Article
- Subcutaneous glucose tracking during extreme perioperative perfusion stress: a prospective microdialysis study.Journal of clinical monitoring and computing · 2026Article
- From Exposure to Outcome: Air Pollution-Induced Oxidative Stress as a Determinant of Early and Late Outcomes After Coronary Artery Bypass Grafting.Antioxidants (Basel, Switzerland) · 2026Review
- Serotonin Signaling and Vascular Reactivity in Cardiometabolic Disease and Cardiac Surgery.Cells · 2026Review
- Discovery of postoperative clinical states linked to cardiac surgery-associated acute kidney injury.BioData mining · 2026Article
- Association Between Rewarming Rate and Short-term Outcomes After Repair of DeBakey Type I Acute Aortic Dissection: A Propensity Score-matched Analysis.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Association of preoperative and postoperative systemic inflammatory markers with early mortality and morbidity after CABG surgery.Journal of cardiothoracic surgery · 2026Article
- Preoperative Glycemic Status in Elective Cardiac Surgery Procedures: HbA1c Independently Predicts Low Cardiac Output Syndrome and Mortality.Diagnostics (Basel, Switzerland) · 2026Article
- Microcirculation dysfunction and cardioprotection in cardiac surgery with cardiopulmonary bypass: mechanisms, monitoring, and therapeutic strategies.Frontiers in cardiovascular medicine · 2026Review
- Pharmacological strategies for myocardial protection in cardiac surgery: current science and the emerging role of multi-omics and artificial intelligence.Frontiers in cardiovascular medicine · 2026Review
- Systemic Anti-Inflammatory and Immunomodulatory Effects of Intravenous Lidocaine During Robotic-Assisted Radical Prostatectomy: A Prospective Observational Study.Medicina (Kaunas, Lithuania) · 2025Observational
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- Article
- The Impact of Basal Inflammatory Status on Post-CABG Atrial and Ventricular Ectopy and Remodeling Pathways.Medicina (Kaunas, Lithuania) · 2025Article
- Cardiopulmonary bypass with deep hypothermic circulatory arrest results in organ-specific transcriptomic responses in pediatric swine.Translational research : the journal of laboratory and clinical medicine · 2025Article
- Microvascular Dysfunction Following Cardioplegic Arrest and Cardiopulmonary Bypass: Impacts of Diabetes and Hypertension.Biomedicines · 2025Review
- Decreased vasoregulatory dysfunction associated with intra-operative hemoadsorption treatment is related to mitigated post-transplant procalcitonin rather than cytokine or complement response.Frontiers in medicine · 2025Article
- A higher preoperative total protein to albumin ratio independently predicted more severe postoperative acute kidney injury in patients with acute type A aortic dissection: a retrospective cohort study of 224 cases.Frontiers in cardiovascular medicine · 2025Article
- Perturbations of tryptophan catabolism via the kynurenine pathway are associated with stage 2 postoperative outcomes in single ventricle heart disease.Physiological reports · 2024Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Despite significant advances in surgical technique and strategies for tissue/organ protection, cardiac surgery involving cardiopulmonary bypass is a profound stressor on the human body and is associated with numerous intraoperative and postoperative collateral effects across different tissues and organ systems. Of note, cardiopulmonary bypass has been shown to induce significant alterations in microvascular reactivity. This involves altered myogenic tone, altered microvascular responsiveness to many endogenous vasoactive agonists, and generalized endothelial dysfunction across multiple vascular beds. This review begins with a survey of
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.