Evidence map›Paper›PMID 36865012›Full record

ArticleClinical kidney journal2023

Risks and outcomes of critical limb ischemia in hemodialysis patients: a prospective cohort study.

Mu-Yang Hsieh, Shao-Yuan Chuang, Chih-Kuo Lee, Chien-Ming Luo, Chi-Hung Cheng, Min-Tsun Liao, Po-Lin Lin, Ten-Fang Yang, Chih-Cheng Wu

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Mu-Yang HsiehDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Shao-Yuan ChuangInstitute of Population Health Science, National Health Research Institutes, Zhunan, Miaoli County, Taiwan.
Chih-Kuo LeeCollege of Medicine, National Taiwan University, Taipei, Taiwan.
Chien-Ming LuoCollege of Medicine, National Taiwan University, Taipei, Taiwan.
Chi-Hung ChengAnsn clinic, Hsinchu, Taiwan.
Min-Tsun LiaoCollege of Medicine, National Taiwan University, Taipei, Taiwan.
Po-Lin LinDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Ten-Fang YangDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Chih-Cheng WuCollege of Medicine, National Taiwan University, Taipei, Taiwan.
National Taiwan University · TWNational Health Research Institutes · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TWTaipei Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Peripheral arterial disease (PAD) is more common in patients receiving maintenance hemodialysis than in the general population. Critical limb ischemia (CLI), the most severe form of PAD, is associated with high amputation and mortality risk. However, few prospective studies are available evaluating this disease's presentation, risk factors and outcomes for patients receiving hemodialysis. Methods: The Hsinchu VA study, a prospective multicentre study, investigated the impact of clinical factors on cardiovascular outcomes of patients receiving maintenance hemodialysis from January 2008 until December 2021. We evaluated the presentations and outcomes of patients with newly diagnosed PAD and the correlations of clinical variables with newly diagnosed CLI. Results: Of 1136 study participants, 1038 had no PAD on enrolment. After a median follow-up period of 3.3 years, 128 had newly diagnosed PAD. Of these, 65 presented with CLI, and 25 underwent amputation or died from PAD. Patients presenting with CLI had more below-the-knee (52%) and multi-level (41%) disease, and completely occluded segments (41%), and higher risk for amputation or PAD-related death compared with patients without CLI (27.7% vs 9.5%, Conclusions: Patients undergoing hemodialysis had higher rates of newly diagnosed CLI than the general population. Those with disabilities, diabetes mellitus, smoking and atrial fibrillation may require careful examination for PAD.

Indexed as

critical limb ischemiadisabilityhemodialysisperipheral artery disease

Identifiers

PMID36865012
PMCPMC9972820
OpenAlexW4311948422

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.