Evidence map›Paper›PMID 36864429›Full record

SynthesisBMC psychiatry2023

Comprehensive ABA-based interventions in the treatment of children with autism spectrum disorder - a meta-analysis.

Theresa Eckes, Ulrike Buhlmann, Heinz-Dieter Holling, Anne Möllmann

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Double-blind, sham-controlled, pilot study of trigeminal nerve stimulation for autism spectrum disorder.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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  17. Trends Over Time in the Prevalence of Autism by Adaptive and Intellectual Functioning Levels.Autism research : official journal of the International Society for Autism Research · 2026
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  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Theresa EckesInstitute of Psychology, University of Münster, Fliednerstr. 21, 48149, Münster, Germany.
Ulrike BuhlmannInstitute of Psychology, University of Münster, Fliednerstr. 21, 48149, Münster, Germany.
Heinz-Dieter HollingInstitute of Psychology, University of Münster, Fliednerstr. 21, 48149, Münster, Germany.
Anne MöllmannInstitute of Psychology, University of Münster, Fliednerstr. 21, 48149, Münster, Germany. moellmann@uni-bremen.de.
University of Münster · DEUniversity of Bremen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany studies display promising results for interventions that are based on Applied Behavior Analysis (ABA) in the treatment of autism spectrum disorder (ASD).

methodsThis meta-analysis assessed the effects of such treatments on developmental outcomes in children with ASD and on parental stress based on 11 studies with 632 participants.

resultsCompared to treatment as usual, minimal or no treatment, comprehensive ABA-based interventions showed medium effects for intellectual functioning (standardized mean difference SMD = 0.51, 95% CI [0.09; 0.92]) and adaptive behavior (SMD = 0.37, 95% CI [0.03; 0.70]). Language abilities, symptom severity or parental stress did not improve beyond the improvement in control groups. Moderator analyses indicate that language abilities at intake could influence the effect sizes and the influence of treatment intensity might decrease with older age.

conclusionsPractical implications and limitations are discussed.

Indexed as

Autism Spectrum DisorderAdaptation, PsychologicalChildCognitionHumansParentsApplied Behavior AnalysisAutism Spectrum DisorderBehavioral TreatmentEarly Intensive Behavioral InterventionsMeta-AnalysisParental Stress

Identifiers

PMID36864429
PMCPMC9983163
OpenAlexW4322767968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.