Evidence map›Paper›PMID 36864360›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

Mike Sathekge, Frank Bruchertseifer, Mariza Vorster, Ismaheel O Lawal, Kgomotso Mokoala, Janet Reed, Letjie Maseremule, Honest Ndlovu, Khanyi Hlongwa, Alex Maes and 2 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Beyond [BMC cancer · 2026
    Pooled it
  2. Evaluating Xerostomia as a side effect of [European journal of nuclear medicine and molecular imaging · 2025
    Pooled it
  3. Pooled it
  4. [Wiener klinische Wochenschrift · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. First-Line [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. The role of PSMA-based radioligand therapy in hormone-sensitive prostate cancer.European journal of nuclear medicine and molecular imaging · 2025
    Review
  13. Advances in PSMA-Targeted Radionuclide Therapeutics.Current treatment options in oncology · 2025
    Review
  14. Article
  15. The [18F] F-PSMA Probe: Chemical Perspectives.Current medicinal chemistry · 2025
    Review
  16. The efficacy and safety ofFrontiers in oncology · 2025
    Article
  17. Review
  18. Review
  19. Review
  20. Design ofAnnals of translational medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Mike SathekgeDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa. mike.sathekge@up.ac.za.ORCID 0000-0002-2806-0625
Frank BruchertseiferEuropean Commission, Joint Research Centre, Karlsruhe, Germany.
Mariza VorsterDepartment of Nuclear Medicine, University of Kwa-Zulu Natal & Inkosi Albert Luthuli Central Academic Hospital, Durban, South Africa.
Ismaheel O LawalDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa.ORCID 0000-0003-4273-040X
Kgomotso MokoalaDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa.
Janet ReedDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa.
Letjie MaseremuleDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa.
Honest NdlovuDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa.
Khanyi HlongwaDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa.
Alex MaesDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa.
Alfred MorgensternDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa.
Christophe Van de WieleDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, 0001, South Africa.
Steve Biko Hospital · ZAGhent University Hospital · BEJoint Research Centre · DEUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose

methodsWe retrospectively reviewed patients with histologically confirmed de novo treatment-naïve bone ± visceral mHSPC that were treated with

resultsTwenty-one mHSPC patients were included in this preliminary work. Following treatment, twenty patients (95%) had any decline in PSA and eighteen patients (86%) presented with a PSA decline of ≥ 50% including 4 patients in whom PSA became undetectable. A lower percentage decrease in PSA following treatment was associated with increased mortality and shorter progression-free survival. Overall, administration of

conclusionsGiven these favorable results, randomized prospective multicenter trials assessing the clinical value of

Indexed as

CarcinomaProstatic Neoplasms, Castration-ResistantActiniumHumansMaleProspective StudiesProstateProstate-Specific AntigenRetrospective StudiesTreatment Outcome(225)Ac-PSMA-617ActiniumProstate-Specific Antigen225Ac-PSMAmHSPCProstate carcinomaPSA responseTherapy response

Identifiers

PMID36864360
PMCPMC10199874
OpenAlexW4323036081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.