Evidence map›Paper›PMID 36864318›Full record

SynthesisJournal of neuro-oncology2023

Prevalence and management of sleep disturbance in adults with primary brain tumours and their caregivers: a systematic review.

Jason A Martin, Nicolas H Hart, Natalie Bradford, Fiona Naumann, Mark B Pinkham, Elizabeth P Pinkham, Justin J Holland

Open access · hybridFull text readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of neuro-oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. The Pinealoprive Syndrome: Myth or Reality?Advances and technical standards in neurosurgery · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jason A MartinFaculty of Health, School of Exercise and Nutrition Science, Queensland University of Technology, Brisbane, Australia. martij23@qut.edu.au.
Nicolas H HartFaculty of Health, School of Sport, Exercise and Rehabilitation, University of Technology Sydney (UTS), Sydney, Australia.
Natalie BradfordFaculty of Health, Cancer and Palliative Care Outcomes Centre, Queensland University of Technology, Brisbane, Australia.
Fiona NaumannFaculty of Health, Southern Cross University, Gold Coast, Australia.
Mark B PinkhamRadiation Oncology, Division of Cancer Services, Princess Alexandra Hospital, Brisbane, Australia.
Elizabeth P PinkhamPhysiotherapy, Clinical Support Services, Princess Alexandra Hospital, Brisbane, Australia.
Justin J HollandFaculty of Health, School of Exercise and Nutrition Science, Queensland University of Technology, Brisbane, Australia.
Queensland University of Technology · AUPrincess Alexandra Hospital · AUEdith Cowan University · AUSouthern Cross University · AU

Funding

National Health and Medical Research Council APP2017080
6 · The paper itself

Abstract

purposeThe aims of this systematic review were to (1) examine the prevalence, severity, manifestations, and clinical associations/risk factors of sleep disturbance in primary brain tumour (PBT) survivors and their caregivers; and (2) determine whether there are any sleep-focused interventons reported in the literature pertaining to people affected by PBT.

methodsThis systematic review was registered with the international register for systematic reviews (PROSPERO: CRD42022299332). PubMed, EMBASE, Scopus, PsychINFO, and CINAHL were electronically searched for relevant articles reporting sleep disturbance and/or interventions for managing sleep disturbance published between September 2015 and May 2022. The search strategy included terms focusing on sleep disturbance, primary brain tumours, caregivers of PBT survivors, and interventions. Two reviewers conducted the quality appraisal (JBI Critical Appraisal Tools) independently, with results compared upon completion.

results34 manuscripts were eligible for inclusion. Sleep disturbance was highly prevalent in PBT survivors with associations between sleep disturbance and some treatments (e.g., surgical resection, radiotherapy, corticosteroid use), as well as other prevalent symptoms (e.g., fatigue, drowsiness, stress, pain). While the current review was unable to find any sleep-targeted interventions, preliminary evidence suggests physical activity may elicit beneficial change on subjectively reported sleep disturbance in PBT survivors. Only one manuscript that discussed caregivers sleep disturbance was identified.

conclusionsSleep disturbance is a prevalent symptom experienced by PBT survivors, yet there is a distinct lack of sleep-focused interventions in this population. This includes a need for future research to include caregivers, with only one study identified. Future research exploring interventions directly focused on the management of sleep disturbance in the context of PBT is warranted.

Indexed as

Brain NeoplasmsSleep Wake DisordersAdultCaregiversHumansPrevalenceSleepCaregiversExerciseNeuro-oncologyPrimary brain tumourQuality of lifeSleep disturbance

Identifiers

PMID36864318
PMCPMC10049936
OpenAlexW4322756139

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read34
measurements read85
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.