Evidence map›Paper›PMID 36864002›Full record

ReviewVirulence2023

Pathogenicity and virulence of monkeypox at the human-animal-ecology interface.

Md Mazharul Islam, Pronesh Dutta, Rijwana Rashid, Syed Shariq Jaffery, Ariful Islam, Elmoubashar Farag, Susu M Zughaier, Devendra Bansal, Mohammad Mahmudul Hassan

Open access · goldFull text readReview
In one paragraph

Review in Virulence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 5 countries.

Md Mazharul IslamDepartment of Animal Resources, Ministry of Municipality, Doha, Qatar.ORCID 0000-0002-7357-9645
Pronesh DuttaFaculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.ORCID 0000-0002-2090-2007
Rijwana RashidFaculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.ORCID 0009-0007-2258-8625
Syed Shariq JafferyDepartment of Health Protection and Communicable Disease Control, Ministry of Public Health, Doha, Qatar.
Ariful IslamEcohealth Alliance, New York, NY, USA.ORCID 0000-0002-9210-3351
Elmoubashar FaragDepartment of Health Protection and Communicable Disease Control, Ministry of Public Health, Doha, Qatar.ORCID 0000-0003-1457-8615
Susu M ZughaierCollege of Medicine, QU Health, Qatar University, Doha, Qatar.ORCID 0000-0001-7487-8770
Devendra BansalDepartment of Health Protection and Communicable Disease Control, Ministry of Public Health, Doha, Qatar.ORCID 0000-0002-1387-4335
Mohammad Mahmudul HassanFaculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh.ORCID 0000-0001-6495-4637
Ministry of Public Health · QAChattogram Veterinary and Animal Sciences University · BDEcoHealth Alliance · USIstanbul Metropolitan Municipality · TRQatar University · QAThe University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monkeypox (Mpox) was mostly limited to Central and Western Africa, but recently it has been reported globally. The current review presents an update on the virus, including ecology and evolution, possible drivers of transmission, clinical features and management, knowledge gaps, and research priorities to reduce the disease transmission. The origin, reservoir(s) and the sylvatic cycle of the virus in the natural ecosystem are yet to be confirmed. Humans acquire the infection through contact with infected animals, humans, and natural hosts. The major drivers of disease transmission include trapping, hunting, bushmeat consumption, animal trade, and travel to endemic countries. However, in the 2022 epidemic, the majority of the infected humans in non-endemic countries had a history of direct contact with clinical or asymptomatic persons through sexual activity. The prevention and control strategies should include deterring misinformation and stigma, promoting appropriate social and behavioural changes, including healthy life practices, instituting contact tracing and management, and using the smallpox vaccine for high-risk people. Additionally, longer-term preparedness should be emphasized using the One Health approach, such as systems strengthening, surveillance and detection of the virus across regions, early case detection, and integrating measures to mitigate the socio-economic effects of outbreaks.

Indexed as

Mpox, MonkeypoxAnimalsDisease OutbreaksEcologyEcosystemHumansMonkeypox virusVirulenceclinical featuresdriversMonkeypoxMpoxone healthprevention and control

Identifiers

PMID36864002
PMCPMC10012937
OpenAlexW4322761522

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read16
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.