Evidence map›Paper›PMID 36863002›Full record

ArticleExpert opinion on investigational drugs2023

The potential role of opioid vaccines and monoclonal antibodies in the opioid overdose crisis.

Suky Martinez, Hannah Harris, Thomas Chao, Rachel Luba, Marco Pravetoni, Sandra D Comer, Jermaine D Jones

Abstract readEditorial
In one paragraph

Article in Expert opinion on investigational drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suky MartinezDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, New York, NY, USA.ORCID 0000-0002-4873-8130
Hannah HarrisDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, New York, NY, USA.
Thomas ChaoBehavioural Reward Affect + Impulsivity Neuroscience Lab, Faculty of Medicine, the University of British Columbia, Vancouver, Bc, Canada.
Rachel LubaDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, New York, NY, USA.ORCID 0000-0003-3404-766X
Marco PravetoniDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.ORCID 0000-0003-1036-0184
Sandra D ComerDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, New York, NY, USA.
Jermaine D JonesDivision on Substance Use Disorders, Columbia University Irving Medical Center & New York State Psychiatric Institute, New York, NY, USA.

Funding

Phase 1a/1b Clinical Trials of Multivalent Opioid Vaccine ComponentsUG3DA047711 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI COMER, SANDRA D, PRAVETONI, MARCO · 2018 to 2019
$9.4M
Translational Clinical Research Fellowship on Substance Use DisordersT32DA007294 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Frances Rudnick Levin, Diana M Martinez · 1993 to 2026
$9.3M
Development of a monoclonal antibody to reverse overdose from fentanyl and its analogs: from manufacturing to clinical trialsUG3DA057850 · NIDA · UNIVERSITY OF WASHINGTON · PI COMER, SANDRA D, PRAVETONI, MARCO · 2022 to 2022
$8.3M
Phase 1a/1b Clinical Trials of Multivalent Opioid Vaccine ComponentsUH3DA047711 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI SANDRA D. COMER, Marco Pravetoni · 2023 to 2026
$7.3M
Vaccines for fentanyl and its derivatives: A strategy to reduce illicit use and overdoseUG3DA048386 · NIDA · UNIVERSITY OF MINNESOTA · PI PRAVETONI, MARCO · 2019 to 2020
$3.3M
NIDA NIH HHS T32 DA007294NIDA NIH HHS UG3 DA047711NIDA NIH HHS UG3 DA048386NIDA NIH HHS UG3 DA057850NIDA NIH HHS UH3 DA047711
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug OverdoseOpiate OverdoseOpioid-Related DisordersAnalgesics, OpioidAntibodies, MonoclonalHumansAnalgesics, OpioidAntibodies, Monoclonalimmunotherapiesmonoclonal antibodiesOpioidsopioid vaccinesoverdose

Identifiers

PMID36863002
PMCPMC10065938

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.