Evidence map›Paper›PMID 36862181›Full record

Observational studyArchives of dermatological research2023

Lower limb cutaneous melanoma surgery: location matters.

Antonio Piñero-Madrona, Pablo Cerezuela-Fuentes, Guadalupe Ruiz-Merino, Enrique Martínez-Barba, Sebastián Ortiz-Reina, María José Martínez-Ortiz, Angel López-Ávila, José F Frías-Iniesta, Alice Viney, Juan Cabezas-Herrera

Registry-linked trialOpen access · hybridAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Archives of dermatological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04625491 (Lower Limb Cutaneous Melanoma), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04625491 unknown statusnot on this map

Lower Limb Cutaneous Melanoma: Observational Prognostic Study About Specific Location of the Primary Lesion.

Typeobservational_patient_registrySponsorHospital Universitario Virgen de la ArrixacaRan2000 to 2021Enrolled300ConditionsCutaneous Melanoma, Anatomical Pathological ConditionArmsObservational
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Antonio Piñero-Madrona *Surgery Department, Hospital Clínico Universitario "Virgen de la Arrixaca", School of Medicine, University of Murcia, Campus de Ciencias de la Salud. Edificio Departamental, Office 4.27, 30120, Murcia, Spain. pinero.madrona@um.es.ORCID http://orcid.org/0000-0002-7718-8318
Pablo Cerezuela-Fuentes *Instituto Murciano de Investigación Biosanitaria (IMIB), Murcia, Spain.
Guadalupe Ruiz-MerinoBiostatistics Department, Fundación para la Formación e Investigación Sanitaria de la Región de Murcia, Murcia, Spain.
Enrique Martínez-BarbaPathology Department, Hospital Clínico Universitario "Virgen de la Arrixaca", Murcia, Spain.
Sebastián Ortiz-ReinaPathology Department, Complejo Hospitalario de Cartagena, Cartagena, Spain.
María José Martínez-OrtizMedical Oncology Department, Complejo Hospitalario de Cartagena, Cartagena, Spain.
Angel López-ÁvilaDermatology Department, Complejo Hospitalario de Cartagena, Cartagena, Spain.
José F Frías-IniestaDermatology Department, Hospital Clínico Universitario "Virgen de la Arrixaca", Murcia, Spain.
Alice VineyPharmacy Department, Complejo Hospitalario de Cartagena, Cartagena, Spain.
Juan Cabezas-HerreraResearch Department, Instituto Murciano de Investigación Biosanitaria (IMIB), Murcia, Spain.
Universidad Politécnica de Cartagena · ESInstituto Murciano de Investigación Biosanitaria · ESHospital Universitario Virgen de la Arrixaca · ESFundación para la Formación e Investigación Sanitarias de la Región de Murcia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anatomical location of cutaneous melanoma is a relevant independent prognostic factor in melanoma. The aim of the study is to know the prognosis of lower limb cutaneous melanoma related to their location within the limb, regardless of the histological type, and if there are any other influencing variables. A real-world data observational study was developed. The lesions were divided depending on the location of the melanoma (thigh, leg and foot). Bivariate and multivariate analysis were performed, and melanoma-specific survival and disease-free survival rates were calculated. When these analysis were done, the results showed that, in melanomas of the lower limb, location on the foot presented a lower melanoma-specific survival rate compared to more proximal locations, and only the anatomical location presents statistical significance to discriminate cases with a higher mortality risk and a lower disease-free survival rate among distal melanomas (mainly on the foot). In conclusion, this study confirms that a more distal location of lower limb cutaneous melanoma is a relevant prognostic factor.Trial registration number NCT04625491 retrospectively registered.

Indexed as

Lower ExtremityMelanomaSkin NeoplasmsAdultAgedCutaneous Malignant MelanomaDisease-Free SurvivalFemaleHumansMaleMiddle AgedPrognosisSpainSurvival RateCutaneous melanomaFootLower limbPrognostic

Identifiers

PMID36862181
PMCPMC10366258
OpenAlexW4322758421

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.