Evidence map›Paper›PMID 36861970›Full record

ArticlemBio2023

Genetic Dissection of Budding Yeast PCNA Mutations Responsible for the Regulated Recruitment of Srs2 Helicase.

Li Fan, Wenqing Zhang, Josephine Rybchuk, Yu Luo, Wei Xiao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Ubiquitin and SUMO pathways in DNA replication and replication-coupled repair.Critical reviews in biochemistry and molecular biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Li FanBeijing Key Laboratory of DNA Damage Responses and College of Life Sciences, Capital Normal University, Beijing, China.
Wenqing ZhangBeijing Key Laboratory of DNA Damage Responses and College of Life Sciences, Capital Normal University, Beijing, China.
Josephine RybchukDepartment of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Yu LuoDepartment of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Wei XiaoBeijing Key Laboratory of DNA Damage Responses and College of Life Sciences, Capital Normal University, Beijing, China.ORCID 0000-0001-7568-0782
University of Saskatchewan · CACapital Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA-damage tolerance (DDT) is a mechanism by which eukaryotes bypass replication-blocking lesions to resume DNA synthesis and maintain cell viability. In Saccharomyces cerevisiae, DDT is mediated by sequential ubiquitination and sumoylation of proliferating cell nuclear antigen (PCNA, encoded by

Indexed as

DNA DamageDNA HelicasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsDNADNA-Binding ProteinsDNA RepairDNA ReplicationMutationProliferating Cell Nuclear AntigenUbiquitin-Protein LigasesDNADNA-Binding ProteinsDNA HelicasesPOL30 protein, S cerevisiaeProliferating Cell Nuclear AntigenRAD5 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsSRS2 protein, S cerevisiaeUbiquitin-Protein Ligasesbudding yeastDNA-damage tolerancePCNAPIP boxRad18Rad5Saccharomyces cerevisiaeSrs2

Identifiers

PMID36861970
PMCPMC10127746
OpenAlexW4322758827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.