Evidence map›Paper›PMID 36861092›Full record

ArticleOpen forum infectious diseases2023

Application of Phage Therapy in a Case of a Chronic Hip-Prosthetic Joint Infection due to

Novella Cesta, Marco Pini, Tiziana Mulas, Alessandro Materazzi, Ernesto Ippolito, Jeroen Wagemans, Mzia Kutateladze, Carla Fontana, Loredana Sarmati, Arianna Tavanti and 3 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. What's New in Musculoskeletal Basic Science.The Journal of bone and joint surgery. American volume · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Antibiotic-ResistantMicroorganisms · 2025
    Review
  15. Review
  16. Multidrug-resistantFrontiers in microbiology · 2025
    Review
  17. Article
  18. Review
  19. Mycobacteriophages and Their Applications.Antibiotics (Basel, Switzerland) · 2024
    Review
  20. Current status of clinical trials for phage therapy.Journal of medical microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Novella CestaMicrobiology, Immunology, Infectious Diseases, and Transplants (MIMIT), University of Rome Tor Vergata, Rome, Italy.ORCID https://orcid.org/0000-0002-8767-7094
Marco PiniDepartment of Biology, University of Pisa, Pisa, Italy.
Tiziana MulasInfectious Diseases Clinic, Policlinic of Tor Vergata, Rome, Italy.
Alessandro MaterazziDepartment of Biology, University of Pisa, Pisa, Italy.
Ernesto IppolitoDepartment of Orthopaedic Surgery, University of Tor Vergata, Rome, Italy.
Jeroen WagemansLaboratory of Gene Technology, Department of Biosystems, KU Leuven, Leuven, Belgium.
Mzia KutateladzeEliava Institute of Bacteriophages, Microbiology and Virology, Tbilisi, Georgia.
Carla FontanaDepartment of Experimental Medicine and Surgery, Unit of Microbiology and Virology, Policlinic of Tor Vergata, Rome, Italy.
Loredana SarmatiInfectious Diseases Clinic, Policlinic of Tor Vergata, Rome, Italy.ORCID https://orcid.org/0000-0003-1452-0333
Arianna TavantiDepartment of Biology, University of Pisa, Pisa, Italy.
Rob LavigneLaboratory of Gene Technology, Department of Biosystems, KU Leuven, Leuven, Belgium.
Massimo AndreoniInfectious Diseases Clinic, Policlinic of Tor Vergata, Rome, Italy.
Mariagrazia Di LucaDepartment of Biology, University of Pisa, Pisa, Italy.
University of Pisa · ITUniversity of Rome Tor Vergata · ITKU Leuven · BEPoliclinico Tor Vergata · ITGeorge Eliava Institute of Bacteriophage, Microbiology and Virology · GE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prosthetic joint infection (PJI) caused by Methods: A 62-year-old woman was affected by a chronic right hip prosthesis infection caused by Results: No severe adverse events were observed during PT. Two years after suspension, there were no clinical signs of infection relapse, and a marked leukocyte scan showed no pathological uptake areas. Conclusions: Personalized PT, in combination with meropenem, was found to be safe and effective in eradicating

Indexed as

biofilmsmeropenemphage therapyprosthetic joint infectionsPseudomonas aeruginosa

Identifiers

PMID36861092
PMCPMC9969736
OpenAlexW4318763457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.