Evidence map›Paper›PMID 36861068›Full record

ArticleInternational journal of pharmaceutics: X2023

Antibiotic-loaded hydroxyapatite scaffolds fabricated from

Atchara Khamkongkaeo, Arreerat Jiamprasertboon, Nanthawan Jinakul, Phatraya Srabua, Saran Tantavisut, Amaraporn Wongrakpanich

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of pharmaceutics: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Atchara KhamkongkaeoDepartment of Metallurgical Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok, Thailand.
Arreerat JiamprasertboonSchool of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
Nanthawan JinakulDepartment of Microbiology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Phatraya SrabuaScientific and Technological Research Equipment Center (STREC), Chulalongkorn University, Bangkok, Thailand.
Saran TantavisutDepartment of Orthopaedics, Chulalongkorn University, Bangkok, Thailand.
Amaraporn WongrakpanichDepartment of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Chulalongkorn University · THMahidol University · THSuranaree University of Technology · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work aimed to develop new antibiotic-coated/ antibiotic-loaded hydroxyapatite (HAp) scaffolds for orthopaedic trauma, specifically to treat the infection after fixation of skeletal fracture. The HAp scaffolds were fabricated from the Nile tilapia (

Indexed as

AntibioticAntibiotic-coatedAntibiotic-loadedCLSI, The Clinical and Laboratory Standards InstituteDI, Deionized waterDMSO, Dimethyl sulfoxideF10[PLGA40-Hvanc], Formulation 10, HAp saffolds containing high concentration of vancomycin, coated with PLGA 40%w/vF11[PLA20-Hvanc], Formulation 11, HAp saffolds containing high concentration of vancomycin, coated with PLA 20%w/vF12[PLA40-Hvanc], Formulation 12, HAp saffolds containing high concentration of vancomycin, coated with PLA 40%w/vF1[V-PLGA20-Lvanc], Formulation 1, HAp saffolds containing low concentration of vancomycin, coated with PLGA 20%w/v blended with vancomycinF2[V-PLGA40-Lvanc], Formulation 2, HAp saffolds containing low concentration of vancomycin, coated with PLGA 40%w/v blended with vancomycinF3[V-PLA20-Lvanc], Formulation 3, HAp saffolds containing low concentration of vancomycin, coated with PLA 20%w/v blended with vancomycinF4[V-PLA40-Lvanc], Formulation 4, HAp saffolds containing low concentration of vancomycin, coated with PLA 40%w/v blended with vancomycinF5[PLGA20-Lvanc], Formulation 5, HAp saffolds containing low concentration of vancomycin, coated with PLGA 20%w/vF6[PLGA40-Lvanc], Formulation 6, HAp saffolds containing low concentration of vancomycin, coated with PLGA 40%w/vF7[PLA20-Lvanc], Formulation 7, HAp saffolds containing low concentration of vancomycin, coated with PLA 20%w/vF8[PLA40-Lvanc], Formulation 8, HAp saffolds containing low concentration of vancomycin, coated with PLA 40%w/vF9[PLGA20-Hvanc], Formulation 9, HAp saffolds containing high concentration of vancomycin, coated with PLGA 20%w/vFDA, Food and Drug AdministrationFTIR, Fourier transforms infrared spectroscopyHAp, HydroxyapatiteHydroxyapatiteIFSF, The infection after fixation of skeletal fractureNile tilapiaPBS, Phosphate-buffered salinePLA, Poly(lactic acid)PLGA, Poly(lactic-co-glycolic acid)P.U., PolyurethanePVA, Polyvinyl alcoholScaffoldSEM, Scanning electron microscopyVancomycinXRD, X-ray diffractionXRF, X-ray fluorescence spectroscopyα-TCP, α-tricalcium phosphateβ-TCP, β-tricalcium phosphate

Identifiers

PMID36861068
PMCPMC9969256
OpenAlexW4319455430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.