Evidence map›Paper›PMID 36861045›Full record

ReviewCritical care explorations2023

Early Versus Delayed Coronary Angiography After Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation-A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Kumait Al Lawati, Ben Forestell, Yasser Binbraik, Sameer Sharif, Craig Ainsworth, Rebecca Mathew, Faizan Amin, Mohammed Al Fawaz, Natalia Pinilla-Echeverri, Emilie Belley-Côté and 2 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Critical care explorations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Kumait Al LawatiDepartment of Medicine, Division of Emergency Medicine, McMaster University, Hamilton, ON, Canada.
Ben ForestellDepartment of Medicine, Division of Emergency Medicine, McMaster University, Hamilton, ON, Canada.
Yasser BinbraikDepartment of Medicine, Division of Critical Care, McMaster University, Hamilton, ON, Canada.
Sameer SharifDepartment of Medicine, Division of Emergency Medicine, McMaster University, Hamilton, ON, Canada.
Craig AinsworthDepartment of Medicine, Division of Critical Care, McMaster University, Hamilton, ON, Canada.
Rebecca MathewDivision of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Faizan AminDepartment of Medicine, Division of Critical Care, McMaster University, Hamilton, ON, Canada.
Mohammed Al FawazDepartment of Medicine, Division of Critical Care, McMaster University, Hamilton, ON, Canada.
Natalia Pinilla-EcheverriDepartment of Medicine, Division of Cardiology, McMaster University, Hamilton, ON, Canada.
Emilie Belley-CôtéDepartment of Medicine, Division of Critical Care, McMaster University, Hamilton, ON, Canada.
Michelle WelsfordDepartment of Medicine, Division of Emergency Medicine, McMaster University, Hamilton, ON, Canada.
Bram RochwergDepartment of Medicine, Division of Critical Care, McMaster University, Hamilton, ON, Canada.
McMaster University · CAImpact · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal timing of coronary angiography remains unclear following out-of-hospital cardiac arrest (OHCA) without ST elevation on electrocardiogram. The objective of this systematic review and meta-analysis was to evaluate the efficacy and safety of early angiography versus delayed angiography following OHCA without ST elevation. DATA SOURCES: The databases MEDLINE, PubMed EMBASE, and CINHAL, as well as unpublished sources from inception to March 9, 2022. STUDY SELECTION: A systematic search was performed for randomized controlled trials of adult patients after OHCA without ST elevation who were randomized to early as compared to delayed angiography. DATA EXTRACTION: Reviewers screened and abstracted data independently and in duplicate. The certainty of evidence was assessed for each outcome using the Grading Recommendations Assessment, Development and Evaluation approach. The protocol was preregistered (CRD 42021292228). DATA SYNTHESIS: Six trials were included (

conclusionsIn OHCA patients without ST elevation, early angiography probably has no effect on mortality and may have no effect on survival with good neurologic outcome and ICU LOS. Early angiography has an uncertain effect on adverse events.

Indexed as

coronary angiographymeta-analysisnon-ST elevated myocardial infarctionout-of-hospital cardiac arrestrandomized controlled trials

Identifiers

PMID36861045
PMCPMC9970266
OpenAlexW4321781556

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.