ArticleNeurobiology of stress2023
Sleep spindles, stress and PTSD: The state of the science and future directions.
Article in Neurobiology of stress, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Sleep to remember, sleep to protect: increased sleep spindle and theta activity predict fewer intrusive memories after analogue trauma.Translational psychiatry · 2026Trial
- Distinct EEG Features and Sleep/Wake Behaviour Predict Anxiety Phenotypes in Mice.Journal of sleep research · 2026Article
- Slow Oscillation-Sleep Spindle Coupling Is Associated With Expectancy Measures of Fear Extinction Retention in Trauma-Exposed Individuals.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- A review of symptom, pathogenesis and treatment characteristics of the elderly with chronic insomnia.Medicine · 2025Review
- Slow oscillation-sleep spindle coupling is associated with fear extinction retention in trauma-exposed individuals.bioRxiv : the preprint server for biology · 2025Article
- Integrative approaches to studying sleep, stress, and related disorders.Neurobiology of stress · 2025Article
- The importance of REM sleep fragmentation in the effects of stress on sleep: Perspectives from preclinical studies.Neurobiology of stress · 2024Article
- Associations of psychological resilience with macro- and microstructures in NREM and REM sleep in adolescents.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Sleep spindles are a signature feature of non-REM (NREM) sleep, with demonstrated relationships to sleep maintenance and learning and memory. Because PTSD is characterized by disturbances in sleep maintenance and in stress learning and memory, there is now a growing interest in examining the role of sleep spindles in the neurobiology of PTSD. This review provides an overview of methods for measuring and detecting sleep spindles as they pertain to human PTSD and stress research, presents a critical review of early findings examining sleep spindles in PTSD and stress neurobiology, and proposes several directions for future research. In doing so, this review underscores the extensive heterogeneity in sleep spindle measurement and detection methods, the wide range of spindle features that may be and have been examined, the many persisting unknowns about the clinical and functional relevance of those features, and the problems considering PTSD as a homogeneous group in between-group comparisons. This review also highlights the progress that has been made in this field and underscores the strong rationale for ongoing work in this area.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.