Evidence map›Paper›PMID 36860986›Full record

ArticleFrontiers in cellular and infection microbiology2023

Leaf hydroalcoholic extract and oleoresin from

Aryani Felixa Fajardo Martínez, Samuel Cota Teixeira, Guilherme de Souza, Alessandra Monteiro Rosini, Joed Pires de Lima Júnior, Gabriel Nogueira Melo, Kelvin Orlando Espinoza Blandón, Angelica Oliveira Gomes, Sergio Ricardo Ambrósio, Rodrigo Cassio Sola Veneziani and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. The Search for Drugs Derived from Natural Products forCurrent topics in medicinal chemistry · 2024
    Pooled it
  2. Pathogens (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Anti-Antioxidants (Basel, Switzerland) · 2025
    Article
  5. Novel drug candidates targetingFrontiers in pharmacology · 2025
    Article
  6. Galectin-3 plays a key role in controlling infection byFrontiers in cellular and infection microbiology · 2024
    Article
  7. Frontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Aryani Felixa Fajardo MartínezLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Samuel Cota TeixeiraLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Guilherme de SouzaLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Alessandra Monteiro RosiniLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Joed Pires de Lima JúniorLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Gabriel Nogueira MeloLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Kelvin Orlando Espinoza BlandónLaboratory of Biology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Angelica Oliveira GomesInstitute of Natural and Biological Sciences, Federal University of Triângulo Mineiro, Uberaba, Brazil.
Sergio Ricardo AmbrósioNucleus of Research in Technological and Exact Sciences, University of Franca, Franca, Brazil.
Rodrigo Cassio Sola VenezianiNucleus of Research in Technological and Exact Sciences, University of Franca, Franca, Brazil.
Jairo Kenupp BastosSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.
Carlos Henrique Gomes MartinsLaboratory of Antimicrobial Testing, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Eloisa Amália Vieira FerroLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Bellisa Freitas BarbosaLaboratory of Immunophysiology of Reproduction, Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.
Universidade Federal de Uberlândia · BRUniversidade de Franca · BRUniversidade de São Paulo · BRUniversidade Federal do Triângulo Mineiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The conventional treatment of congenital toxoplasmosis is mainly based on the combination of sulfadiazine and pyrimethamine. However, therapy with these drugs is associated with severe side effects and resistance, requiring the study of new therapeutic strategies. There are currently many studies with natural products, including

Indexed as

FabaceaeToxoplasmosis, CongenitalAntiparasitic AgentsCytokinesFemaleHumansPlacentaPlant ExtractsPregnancyPregnancy Trimester, ThirdTrophoblastsAntiparasitic AgentsCytokinesoleoresinsPlant Extractscongenital toxoplasmosis (CT)Copaifera multijugahydroalcoholic extractoleoresinToxoplasma gondiitrophoblast

Identifiers

PMID36860986
PMCPMC9970041
OpenAlexW4320495268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.