Evidence map›Paper›PMID 36860838›Full record

ArticleRadiology. Cardiothoracic imaging2023

Fetal Cardiac Cine MRI with Doppler US Gating in Complex Congenital Heart Disease.

Thomas M Vollbrecht, Christopher Hart, Shuo Zhang, Christoph Katemann, Alexander Isaak, Claus C Pieper, Daniel Kuetting, Bettina Faridi, Brigitte Strizek, Ulrike Attenberger and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
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  4. Feasibility of fetal cardiac function and anatomy assessment by real-time spiral balanced steady-state free precession magnetic resonance imaging at 0.55T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
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  9. Radiology. Cardiothoracic imaging · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Thomas M VollbrechtDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0002-1162-2839
Christopher HartDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0001-5880-3576
Shuo ZhangDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0002-1057-7255
Christoph KatemannDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0002-5199-0644
Alexander IsaakDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0003-2016-6166
Claus C PieperDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0002-0893-1200
Daniel KuettingDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0001-6520-1020
Bettina FaridiDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).
Brigitte StrizekDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0003-3625-7097
Ulrike AttenbergerDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0002-8123-5447
Florian KipfmuellerDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0002-7414-757X
Ulrike HerbergDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).
Annegret GeipelDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).
Julian A LuetkensDepartments of Diagnostic and Interventional Radiology (T.M.V., C.H., A.I., C.C.P., D.K., U.A., J.A.L.), Pediatric Cardiology (C.H., U.H.), Obstetrics and Prenatal Medicine (B.F., B.S., A.G.), and Neonatology and Pediatric Intensive Care Medicine (F.K.), University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany; Quantitative Imaging Laboratory Bonn (QILaB) (T.M.V., C.H., A.I., D.K., J.A.L.), Bonn, Germany; and Philips GmbH Market DACH, Hamburg, Germany (S.Z., C.K.).ORCID https://orcid.org/0000-0002-7715-4636
University Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To apply Doppler US (DUS)-gated fetal cardiac cine MRI in clinical routine and investigate diagnostic performance in complex congenital heart disease (CHD) compared with that of fetal echocardiography. Materials and Methods: In this prospective study (May 2021 to March 2022), women with fetuses with CHD underwent fetal echocardiography and DUS-gated fetal cardiac MRI on the same day. For MRI, balanced steady-state free precession cine images were acquired in the axial and optional sagittal and/or coronal orientations. Overall image quality was assessed on a four-point Likert scale (from 1 = nondiagnostic to 4 = good image quality). The presence of abnormalities in 20 fetal cardiovascular features was independently assessed by using both modalities. The reference standard was postnatal examination results. Differences in sensitivities and specificities were determined by using a random-effects model. Results: The study included 23 participants (mean age, 32 years ± 5 [SD]; mean gestational age, 36 weeks ± 1). Fetal cardiac MRI was completed in all participants. The median overall image quality of DUS-gated cine images was 3 (IQR, 2.5-4). In 21 of 23 participants (91%), underlying CHD was correctly assessed by using fetal cardiac MRI. In one case, the correct diagnosis was made by using MRI only (situs inversus and congenitally corrected transposition of the great arteries). Sensitivities (91.8% [95% CI: 85.7, 95.1] vs 93.6% [95% CI: 88.8, 96.2]; Conclusion: Using DUS-gated fetal cine cardiac MRI resulted in performance comparable with that of using fetal echocardiography for diagnosing complex fetal CHD.

Indexed as

CardiacCardiac MRICongenitalCongenital Heart DiseaseFetal ImagingHeartMR-Fetal (Fetal MRI)PediatricsPrenatal

Identifiers

PMID36860838
PMCPMC9969216
OpenAlexW4321613845

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.