Evidence map›Paper›PMID 36860834›Full record

ArticleRadiology. Cardiothoracic imaging2023

Effects of Mitral Valve Prolapse on Quantification of Mitral Regurgitation and Ejection Fraction Using Cardiac MRI.

Bamidele T Otemuyiwa, Elizabeth M Lee, Edith Sella, Chaitanya Madamanchi, Sowmya Balasubramanian, Tianwen Ma, Aparna Joshi, Jimmy C Lu, Adam L Dorfman, Prachi Agarwal

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Bamidele T OtemuyiwaDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).ORCID 0000-0002-2359-2972
Elizabeth M LeeDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).ORCID 0000-0001-5404-1447
Edith SellaDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).ORCID 0000-0002-7260-9128
Chaitanya MadamanchiDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).
Sowmya BalasubramanianDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).
Tianwen MaDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).ORCID 0000-0003-2741-7706
Aparna JoshiDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).
Jimmy C LuDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).ORCID 0000-0002-2544-7402
Adam L DorfmanDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).ORCID 0000-0002-1229-3774
Prachi AgarwalDepartment of Radiology (B.T.O.), Department of Radiology, Cardiothoracic Radiology Division (E.M.L., E.S., P.A.), Department of Cardiology (C.M.), Department of Pediatrics, Pediatric Cardiology Division (S.B., J.C.L., A.L.D.), and Department of Radiology, Pediatric Radiology Division (A.J.), University of Michigan Medical Center, 1500 E Medical Center Dr, B1D502, Ann Arbor, MI 48109-5030; and School of Public Health, University of Michigan, Ann Arbor, Mich (T.M.).ORCID https://orcid.org/0000-0002-4439-6970
Michigan Medicine · US

Funding

Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary HypertensionU01HL135842 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BAEK, SEUNGIK, DORFMAN, ADAM LEE · 2017 to 2020
$2.3M
NHLBI NIH HHS U01 HL135842
6 · The paper itself

Abstract

Purpose: To determine the impact of prolapsed volume on regurgitant volume (RegV), regurgitant fraction (RF), and left ventricular ejection fraction (LVEF) in patients with mitral valve prolapse (MVP) using cardiac MRI. Materials and Methods: Patients with MVP and mitral regurgitation who underwent cardiac MRI from 2005 to 2020 were identified retrospectively from the electronic record. RegV is the difference between left ventricular stroke volume (LVSV) and aortic flow. Left ventricular end-systolic volume (LVESV) and LVSV were obtained from volumetric cine images, with prolapsed volume inclusion (LVESVp, LVSVp) and exclusion (LVESVa, LVSVa) providing two estimates of RegV (RegVp, RegVa), RF (RFp, RFa), and LVEF (LVEFa, LVEFp). Interobserver agreement for LVESVp was assessed using intraclass correlation coefficient (ICC). RegV was also calculated independently using measurements from mitral inflow and aortic net flow phase-contrast imaging as the reference standard (RegVg). Results: The study included 19 patients (mean age, 28 years ± 16 [SD]; 10 male patients). Interobserver agreement for LVESVp was high (ICC, 0.98; 95% CI: 0.96, 0.99). Prolapsed volume inclusion resulted in higher LVESV (LVESVp: 95.4 mL ± 34.7 vs LVESVa: 82.4 mL ± 33.8; Conclusion: Measurements that included prolapsed volume most closely reflected mitral regurgitation severity, but inclusion of this volume resulted in a lower LVEF.

Indexed as

CardiacMRI

Identifiers

PMID36860834
PMCPMC9969218
OpenAlexW4321118310

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.