Evidence map›Paper›PMID 36860665›Full record

ArticleFrontiers in molecular neuroscience2023

Paclitaxel effects on axonal localization and vesicular trafficking of Na

Christopher A Baker, Sidharth Tyagi, Grant P Higerd-Rusli, Shujun Liu, Peng Zhao, Fadia B Dib-Hajj, Stephen G Waxman, Sulayman D Dib-Hajj

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. A topical nociceutical formulation ameliorates chemotherapy-induced peripheral neuropathy: a pilot randomized clinical study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Trial
  2. Review
  3. Article
  4. Review
  5. Nav1.8, an analgesic target for nonpsychotomimetic phytocannabinoids.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Christopher A BakerDepartment of Neurology, Yale University, New Haven, CT, United States.
Sidharth TyagiDepartment of Neurology, Yale University, New Haven, CT, United States.
Grant P Higerd-RusliDepartment of Neurology, Yale University, New Haven, CT, United States.
Shujun LiuDepartment of Neurology, Yale University, New Haven, CT, United States.
Peng ZhaoDepartment of Neurology, Yale University, New Haven, CT, United States.
Fadia B Dib-HajjDepartment of Neurology, Yale University, New Haven, CT, United States.
Stephen G WaxmanDepartment of Neurology, Yale University, New Haven, CT, United States.
Sulayman D Dib-HajjDepartment of Neurology, Yale University, New Haven, CT, United States.
VA Connecticut Healthcare System · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
BLRD VA I01 BX004899NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Patients treated with paclitaxel (PTX) or other antineoplastic agents can experience chemotherapy-induced peripheral neuropathy (CIPN), a debilitating side effect characterized by numbness and pain. PTX interferes with microtubule-based transport, which inhibits tumor growth

Indexed as

chemotherapyneuropathypaclitaxelpainsodium channels

Identifiers

PMID36860665
PMCPMC9970094
OpenAlexW4320494413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.